SCHEMBL2178199

SCHEMBL2178199

BrCCc1cccc2nc(-c3ccccc3)[nH]c12

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 5/20 0.47
RAB9A P51151 5/20 0.47
GAA P10253 2/20 0.47
TNKS O95271 2/20 0.44
TNKS2 Q9H2K2 2/20 0.44
PARP1 P09874 1/20 0.44
CYP1A1 P04798 1/20 0.39
CYP1B1 Q16678 1/20 0.39
ALDH1A1 P00352 6/20 0.38
KDM4E B2RXH2 5/20 0.38
HPGD P15428 5/20 0.38
MAPT P10636 3/20 0.38
HSD17B10 Q99714 3/20 0.38
SMN1; SMN2 Q16637 3/20 0.38
TP53 P04637 2/20 0.38
ADORA3 P0DMS8 1/20 0.38
ADORA2A P29274 1/20 0.38
ADORA1 P30542 1/20 0.38
GLA P06280 1/20 0.38
HTT P42858 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2176986 0.85 NPC1 (0.47) NPC1RAB9AGAATNKSTNKS2
SCHEMBL9663560 0.81 NPC1 (0.50) NPC1RAB9AGAATNKSTNKS2
SCHEMBL28306367 0.81 NPC1 (0.50) NPC1RAB9AGAATNKSTNKS2
SCHEMBL29829731 0.77 ALDH1A1 (0.50) NPC1RAB9AGAAALDH1A1KDM4E
SCHEMBL7210788 0.76 GRIN2B (0.58) NPC1RAB9AGAAPARP1ALDH1A1
SCHEMBL5939 0.76 NPC1 (0.55) NPC1RAB9AGAATNKSTNKS2
SCHEMBL27761849 0.74 NPC1 (0.56) NPC1RAB9AGAATNKSTNKS2
SCHEMBL18300831 0.72 NPC1 (0.55) NPC1RAB9AGAATNKSTNKS2
SCHEMBL6368201 0.72 NPC1 (0.55) NPC1RAB9AGAATNKSTNKS2
SCHEMBL56854 0.72 RAB9A (0.55) NPC1RAB9AGAATNKSTNKS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8703243-B2 Anti-tarnish coatings ENTHONE INC. (US) 2014-04-22 US claimed
US-20120175022-A1 ANTI-TARNISH COATINGS ENTHONE INC. (US) 2012-07-12 US claimed
US-7972655-B2 Anti-tarnish coatings ENTHONE INC. (US) 2011-07-05 US claimed
US-20100291303-A1 ANTI-TARNISH COATINGS ENTHONE INC. (US) 2010-11-18 US claimed
EP-2220009-A1 ANTI-TARNISH COATING Enthone, Inc. (US) 2010-08-25 EP claimed
WO-2009067446-A1 ANTI-TARNISH COATING ENTHONE INC. (US) 2009-05-28 WO claimed
EP-1097618-B1 POST-TREATMENT FOR COPPER ON PRINTED CIRCUIT BOARDS FRYS METALS INC DBA ALPHA METALS INC (US) 2003-03-26 EP claimed
US-6294220-B1 IMPROVED CHEMICAL RESISTANCE CAN BE ACCOMPLISHED BY CONVERTING MOST OF THE CUPRIC-BASED ORGANOMETALLIC COMPOUND ON THE SURFACE INTO A CUPROUS-BASED ORGANOMETALLIC CONVERSION COATING. ALPHA METALS, INC. 2001-09-25 US claimed
EP-1097618-A1 POST-TREATMENT FOR COPPER ON PRINTED CIRCUIT BOARDS FRY'S METALS, INC. d/b/a ALPHA METALS, INC. (US) 2001-05-09 EP claimed
WO-2000002426-A1 POST-TREATMENT FOR COPPER ON PRINTED CIRCUIT BOARDS FRY'S METALS, INC. D/B/A ALPHA METALS, INC. (US) 2000-01-13 WO claimed
US-5362334-A Chemically forming protective layer on metal surface by treating with aqueous solution of benzimidazole 2-substituted with halogen, haloalkyl or haloaryl MACDERMID, INCORPORATED (US) 1994-11-08 US claimed
EP-2142485-B1 METALLIC SURFACE ENHANCEMENT MACDERMID ENTHONE INC (US) 2019-07-24 EP disclosed
US-9865952-B2 Plug contact with organic coating and printed circuit board arrangement CONTINENTAL AUTOMOTIVE GMBH (DE) 2018-01-09 US disclosed
US-20170179628-A1 PLUG CONTACT WITH ORGANIC COATING AND PRINTED CIRCUIT BOARD ARRANGEMENT CONTINENTAL AUTOMOTIVE GMBH (DE) 2017-06-22 US disclosed
CN-102548248-B Printed circuit board and manufacturing method thereof SAMSUNG ELECTRO-MECHANICS CO.,LTD. (KR) 2016-01-20 CN disclosed
US-20030209523-A1 Planarization by chemical polishing for ULSI applications APPLIED MATERIALS, INC. 2003-11-13 US disclosed
EP-1097618-B1 POST-TREATMENT FOR COPPER ON PRINTED CIRCUIT BOARDS FRYS METALS INC DBA ALPHA METALS INC (US) 2003-03-26 EP disclosed
US-6294220-B1 IMPROVED CHEMICAL RESISTANCE CAN BE ACCOMPLISHED BY CONVERTING MOST OF THE CUPRIC-BASED ORGANOMETALLIC COMPOUND ON THE SURFACE INTO A CUPROUS-BASED ORGANOMETALLIC CONVERSION COATING. ALPHA METALS, INC. 2001-09-25 US disclosed
EP-1097618-A1 POST-TREATMENT FOR COPPER ON PRINTED CIRCUIT BOARDS FRY'S METALS, INC. d/b/a ALPHA METALS, INC. (US) 2001-05-09 EP disclosed
WO-2000002426-A1 POST-TREATMENT FOR COPPER ON PRINTED CIRCUIT BOARDS FRY'S METALS, INC. D/B/A ALPHA METALS, INC. (US) 2000-01-13 WO disclosed