Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 1/20 | 0.35 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.35 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.35 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.35 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.35 |
| ▸ | NPY4R | P50391 | 6/20 | 0.33 |
| ▸ | NPY1R | P25929 | 4/20 | 0.33 |
| ▸ | TLR2 | O60603 | 4/20 | 0.32 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.32 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.31 |
| ▸ | NPY2R | P49146 | 3/20 | 0.31 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21782583 | 0.82 | NPY4R (0.46) | GNAI3GNAO1GNAI1SIRT6SIRT1 | |
| SCHEMBL21782630 | 0.76 | GNAI3 (0.39) | GNAI3GNAO1GNAI1SIRT6SIRT1 | |
| SCHEMBL21782581 | 0.73 | DPP7 (0.38) | GNAI3GNAO1GNAI1SIRT6SIRT1 | |
| SCHEMBL21782713 | 0.73 | NPY4R (0.38) | NPY4RNPY1RPAOXNPY2RNPY5R | |
| SCHEMBL5974381 | 0.70 | NPY4R (0.37) | SIRT6SIRT1NPY4RNPY1RTLR2 | |
| SCHEMBL10792564 | 0.70 | NPY4R (0.57) | GNAI3GNAO1GNAI1SIRT6SIRT1 | |
| SCHEMBL10792547 | 0.70 | NPY4R (0.57) | GNAI3GNAO1GNAI1SIRT6SIRT1 | |
| SCHEMBL16263595 | 0.70 | NPY4R (0.48) | GNAI3GNAO1GNAI1SIRT6SIRT1 | |
| SCHEMBL21782580 | 0.70 | DPP7 (0.36) | GNAI3GNAO1GNAI1SIRT6SIRT1 | |
| SCHEMBL5976008 | 0.70 | NPY4R (0.33) | GNAI3GNAO1GNAI1SIRT6SIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2753613-B1 | DERIVATIVES OF XANTHONE COMPOUNDS | AGENCY SCIENCE TECH & RES (SG) | 2020-03-04 | — | — | EP | disclosed |