Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | FUCA1 | P04066 | 2/20 | 0.33 |
| ▸ | AHCY | P23526 | 2/20 | 0.31 |
| ▸ | M6PR | P20645 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16327272 | 0.98 | CA2 (0.38) | CA9CA12CA2FUCA1AHCY | |
| SCHEMBL13699579 | 0.98 | CA2 (0.38) | CA9CA12CA2FUCA1AHCY | |
| SCHEMBL13498556 | 0.98 | CA2 (0.38) | CA9CA12CA2FUCA1AHCY | |
| SCHEMBL13887631 | 0.98 | CA2 (0.38) | CA9CA12CA2FUCA1AHCY | |
| SCHEMBL24599501 | 0.86 | CA9 (0.33) | CA9CA12CA2FUCA1 | |
| SCHEMBL12900024 | 0.78 | M6PR (0.33) | CA9CA12CA2M6PR | |
| SCHEMBL19401511 | 0.76 | M6PR (0.33) | M6PR | |
| SCHEMBL12899760 | 0.75 | FUCA1 (0.33) | CA9CA12CA2FUCA1 | |
| SCHEMBL16556765 | 0.75 | FUCA1 (0.33) | CA9CA12CA2FUCA1 | |
| SCHEMBL16076954 | 0.75 | ALDH1A1 (0.34) | FUCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3029041-B1 | INHIBITORS OF HUMAN PHOSPHATIDYL-INOSITOL 3-KINASE DELTA | ICOS CORP (US) | 2020-03-04 | — | — | EP | disclosed |