SCHEMBL21782853

SCHEMBL21782853

C1=CC(Oc2nccc3ccccc23)=CCC1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.45
PLAU P00749 2/20 0.38
CYP2A6 P11509 1/20 0.38
F12 P00748 1/20 0.38
NCF1 P14598 1/20 0.38
NOS3 P29474 1/20 0.38
NOS1 P29475 1/20 0.38
NOS2 P35228 1/20 0.38
BACE1 P56817 1/20 0.38
FFAR1 O14842 1/20 0.36
LMNA P02545 1/20 0.35
KLK5 Q9Y337 1/20 0.34
DRD1 P21728 4/20 0.34
HRH4 Q9H3N8 1/20 0.33
HTR2C P28335 1/20 0.33
PLG P00747 1/20 0.33
SSTR1 P30872 1/20 0.32
SSTR4 P31391 1/20 0.32
MAPT P10636 2/20 0.32
NPC1 O15118 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31498832 0.77 TRPA1 (0.60) TRPA1PLAUCYP2A6F12NCF1
SCHEMBL6110247 0.77 TRPA1 (0.60) TRPA1PLAUCYP2A6F12NCF1
SCHEMBL9849057 0.75 HTR1B (0.38) MAPTALDH1A1RAB9AHSD17B10
SCHEMBL4107863 0.71 MAPT (0.42) PLAUCYP2A6F12NCF1NOS3
SCHEMBL1093339 0.71 TRPA1 (0.54) TRPA1PLAUCYP2A6F12NCF1
SCHEMBL7826992 0.68 ACHE (0.39) PLAUCYP2A6F12NCF1NOS3
SCHEMBL7540308 0.67
SCHEMBL10273562 0.67 LTA4H (0.44) MAPT
SCHEMBL2231183 0.67 CYP2A6 (0.55) TRPA1PLAUCYP2A6F12NCF1
SCHEMBL11666789 0.67 PLAU (0.50) TRPA1PLAUCYP2A6F12NCF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3617216-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND DIAGNOSTIC COMPOSITION INCLUDING THE ORGANOMETALLIC COMPOUND Samsung Electronics Co., Ltd. (KR) 2020-03-04 EP disclosed