Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.33 |
| ▸ | LSS | P48449 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21782877 | 0.89 | DPP4 (0.41) | CA12CA1CA2CA9KMT2A | |
| SCHEMBL24556352 | 0.85 | CA12 (0.47) | CA12CA1CA2CA9KMT2A | |
| SCHEMBL12763881 | 0.79 | MEN1 (0.57) | CA12CA1CA2CA9KMT2A | |
| SCHEMBL22540331 | 0.77 | MEN1 (0.31) | KMT2AMEN1POLBMAPT | |
| SCHEMBL3306436 | 0.76 | L3MBTL1 (0.43) | KMT2AMEN1POLBMAPTSMN1; SMN2 | |
| SCHEMBL13366383 | 0.75 | CA12 (0.52) | CA12CA1CA2CA9KMT2A | |
| SCHEMBL3308433 | 0.74 | L3MBTL1 (0.45) | KMT2AMEN1SMN1; SMN2ALDH1A1 | |
| Butane SCHEMBL28217400 | 0.73 | CA12 (0.46) | CA12CA1CA2CA9KMT2A | |
| SCHEMBL31542034 | 0.72 | MEN1 (0.71) | KMT2AMEN1POLBMAPTALDH1A1 | |
| SCHEMBL18738461 | 0.71 | CHRM1 (0.38) | KMT2AMEN1POLBMAPTCHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3402783-B1 | 3-(CARBOXYETHYL)-8-AMINO-2-OXO-1,3-DIAZA-SPIRO-[4.5]-DECANE DERIVATIVES | GRUENENTHAL GMBH (DE) | 2020-03-04 | — | — | EP | disclosed |