Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.31 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.31 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.30 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.30 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21782914 | 0.89 | CA12 (0.44) | DPP4CA12CA1CA2CA9 | |
| SCHEMBL22540331 | 0.84 | MEN1 (0.31) | MEN1POLBMAPTKMT2A | |
| SCHEMBL24114571 | 0.80 | DPP4 (0.36) | DPP4DPP7 | |
| SCHEMBL9216541 | 0.77 | CHRNB2 (0.50) | DPP4DPP7CHRM2CHRM4CHRM1 | |
| SCHEMBL11892683 | 0.77 | CHRNB2 (0.50) | DPP4DPP7CHRM2CHRM4CHRM1 | |
| SCHEMBL9221110 | 0.77 | CHRNB2 (0.50) | DPP4DPP7CHRM2CHRM4CHRM1 | |
| SCHEMBL25824843 | 0.76 | NPC1 (0.47) | LMNAMEN1POLBMAPTKMT2A | |
| SCHEMBL19934605 | 0.75 | GAA (0.31) | MAPT | |
| SCHEMBL24712346 | 0.75 | DPP7 (0.51) | DPP4DPP7LMNAGNAI3GNAO1 | |
| SCHEMBL24556352 | 0.73 | CA12 (0.47) | DPP4CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3402783-B1 | 3-(CARBOXYETHYL)-8-AMINO-2-OXO-1,3-DIAZA-SPIRO-[4.5]-DECANE DERIVATIVES | GRUENENTHAL GMBH (DE) | 2020-03-04 | — | — | EP | disclosed |