Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GBA1 | P04062 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21782877 | 0.84 | DPP4 (0.41) | MEN1POLBMAPTKMT2A | |
| SCHEMBL21782914 | 0.77 | CA12 (0.44) | MEN1POLBMAPTKMT2A | |
| SCHEMBL25824843 | 0.76 | NPC1 (0.47) | MEN1POLBMAPTKMT2ANPC1 | |
| SCHEMBL12847052 | 0.71 | CHRNB2 (0.43) | MEN1POLBMAPTKMT2ANPC1 | |
| SCHEMBL19934605 | 0.71 | GAA (0.31) | MAPT | |
| SCHEMBL18738461 | 0.70 | CHRM1 (0.38) | MEN1POLBMAPTKMT2A | |
| SCHEMBL26495122 | 0.69 | NPC1 (0.32) | MEN1POLBMAPTKMT2ANPC1 | |
| SCHEMBL14224955 | 0.69 | MEN1 (0.47) | MEN1POLBMAPTKMT2ANPC1 | |
| SCHEMBL21195937 | 0.68 | CA1 (0.34) | MEN1KMT2ANPC1 | |
| SCHEMBL18497723 | 0.68 | CA1 (0.34) | MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3722283-A1 | 3-(CARBOXYETHYL)-8-AMINO-2-OXO-1,3-DIAZA-SPIRO-[4.5]-DECANE DERIVATIVES | Grünenthal GmbH (DE) | 2020-10-14 | — | — | EP | disclosed |