Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.68 |
| ▸ | MAPT | P10636 | 4/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.67 |
| ▸ | PPARG | P37231 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.54 |
| ▸ | IDH1 | O75874 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | IDE | P14735 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21783132 | 0.90 | ALDH1A1 (0.82) | ALDH1A1MAPTMAPK1PPARGLMNA | |
| SCHEMBL20534419 | 0.87 | ALDH1A1 (0.63) | ALDH1A1MAPTMAPK1LMNAPSMB5 | |
| SCHEMBL20534342 | 0.87 | ALDH1A1 (0.63) | ALDH1A1MAPTMAPK1LMNAPSMB5 | |
| SCHEMBL20534417 | 0.87 | ALDH1A1 (0.63) | ALDH1A1MAPTMAPK1LMNAPSMB5 | |
| SCHEMBL9682018 | 0.81 | ALDH1A1 (0.67) | ALDH1A1MAPTMAPK1PPARGLMNA | |
| SCHEMBL9682014 | 0.81 | ALDH1A1 (0.67) | ALDH1A1MAPTMAPK1PPARGLMNA | |
| SCHEMBL16536031 | 0.78 | ALDH1A1 (0.77) | ALDH1A1MAPTMAPK1PPARGLMNA | |
| SCHEMBL16536033 | 0.78 | ALDH1A1 (0.77) | ALDH1A1MAPTMAPK1PPARGLMNA | |
| SCHEMBL21783156 | 0.77 | PPARG (0.79) | ALDH1A1MAPTMAPK1PPARGMEN1 | |
| SCHEMBL20534545 | 0.76 | ALDH1A1 (0.79) | ALDH1A1MAPTLMNAPSMB5GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200068890-A1 | HETEROCYCLIC INHIBITORS OF LYSINE BIOSYNTHESIS VIA THE DIAMINOPIMELATE PATHWAY | LA TROBE UNIVERSITY (AU) | 2020-03-05 | — | — | US | disclosed |
| CN-110621315-A | Heterocyclic inhibitors of lysine biosynthesis via the diaminopimelic acid pathway | 拉筹伯大学 | 2019-12-27 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200068890-A1 | HETEROCYCLIC INHIBITORS OF LYSINE BIOSYNTHESIS VIA THE DIAMINOPIMELATE PATHWAY | DDC, ODC1, DDT | ALDH1A1 461/4885MAPT 3729/4885MAPK1 463/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.