Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | TOP2A | P11388 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | CASP9 | P55211 | 1/20 | 0.41 |
| ▸ | BAX | Q07812 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.36 |
| ▸ | PIK3R1 | P27986 | 3/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1387509 | 0.78 | KDM4E (0.75) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL8983611 | 0.74 | KDM4E (0.78) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL9500971 | 0.73 | KDM4E (0.81) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL21783203 | 0.73 | KDM4E (0.53) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL13923333 | 0.72 | KDM4E (0.79) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL10028895 | 0.72 | KDM4E (0.82) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| Ciprofloxacin SCHEMBL9788113 | 0.72 | KDM4E (0.92) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| Ciprofloxacin Ethyl Ester SCHEMBL6779201 | 0.71 | KDM4E (0.74) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL26017122 | 0.71 | KDM4E (0.77) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| Ciprofloxacin SCHEMBL10392202 | 0.71 | KDM4E (0.94) | KDM4EALDH1A1LMNAHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020014269-A9 | BISPHOSPHONATE QUINOLONE CONJUGATES AND USES THEREOF | BIOVINC, LLC. (US) | 2020-03-05 | — | — | WO | disclosed |