Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | TACR1 | P25103 | 1/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.33 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | OGA | O60502 | 1/20 | 0.33 |
| ▸ | TACR2 | P21452 | 1/20 | 0.32 |
| ▸ | GJB2 | P29033 | 1/20 | 0.32 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21783252 | 0.79 | BCHE (0.44) | BCHEACHEPDE4DPDPK1MTOR | |
| SCHEMBL21783194 | 0.77 | BCHE (0.52) | BCHEACHEPDE4DPDPK1MTOR | |
| SCHEMBL21783250 | 0.77 | BCHE (0.47) | BCHEACHEPDE4DPDPK1MTOR | |
| SCHEMBL21783309 | 0.75 | NPSR1 (0.39) | BCHEACHEPDE4DPDPK1MTOR | |
| SCHEMBL21783181 | 0.74 | BCHE (0.46) | BCHEACHEPDE4DPDPK1MTOR | |
| SCHEMBL21783307 | 0.74 | BCHE (0.46) | BCHEACHEPDE4DPDPK1MTOR | |
| SCHEMBL22729197 | 0.72 | BCHE (0.39) | BCHEACHEPDE4DTACR1PSEN1 | |
| SCHEMBL24437953 | 0.71 | BCHE (0.50) | BCHEACHEPDE4DPDPK1MTOR | |
| SCHEMBL14696978 | 0.70 | BCHE (0.50) | BCHEACHEPDE4DPDPK1MTOR | |
| SCHEMBL21783270 | 0.70 | BCHE (0.49) | BCHEACHEPDE4DPDPK1MTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020046132-A1 | PHARMACOLOGICAL CHAPERONES FOR ENZYME TREATMENT THERAPY | LEIDEN UNIVERSITY (NL) | 2020-03-05 | — | — | WO | disclosed |