Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.38 |
| ▸ | BCHE | P06276 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | KLK7 | P49862 | 6/20 | 0.37 |
| ▸ | KLK5 | Q9Y337 | 4/20 | 0.37 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.34 |
| ▸ | CDC25A | P30304 | 2/20 | 0.34 |
| ▸ | CDC25B | P30305 | 2/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.33 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21783251 | 0.75 | BCHE (0.44) | BCHEACHEPDPK1MTORPDE4D | |
| SCHEMBL22729197 | 0.72 | BCHE (0.39) | BCHEACHEKLK7KLK5PDE4D | |
| SCHEMBL21783181 | 0.71 | BCHE (0.46) | BCHEACHEPDPK1MTORPDE4D | |
| SCHEMBL21783194 | 0.70 | BCHE (0.52) | BCHEACHEPDPK1MTORPDE4D | |
| SCHEMBL30001622 | 0.70 | KLK5 (0.45) | L3MBTL1BCHEACHEKLK7KLK5 | |
| SCHEMBL23181294 | 0.69 | HDAC3 (0.38) | NPSR1L3MBTL1HSD11B1 | |
| SCHEMBL21783307 | 0.69 | BCHE (0.46) | BCHEACHEPDPK1MTORPDE4D | |
| SCHEMBL22756279 | 0.68 | KMT2A (0.52) | L3MBTL1KLK7KLK5PTPN2PTPN1 | |
| SCHEMBL22729198 | 0.68 | KMT2A (0.52) | L3MBTL1KLK7KLK5PTPN2PTPN1 | |
| SCHEMBL6409534 | 0.68 | L3MBTL1 (0.43) | L3MBTL1KLK7KLK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020046132-A1 | PHARMACOLOGICAL CHAPERONES FOR ENZYME TREATMENT THERAPY | LEIDEN UNIVERSITY (NL) | 2020-03-05 | — | — | WO | disclosed |