Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN1A | P35498 | 1/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21783392 | 0.80 | SCN8A (0.32) | SCN1ASCN5ASCN8ARIPK1 | |
| SCHEMBL21955474 | 0.80 | SCN8A (0.32) | SCN1ASCN5ASCN8ARIPK1 | |
| SCHEMBL21783394 | 0.74 | SCN1A (0.35) | SCN1ASCN5ASCN8ARIPK1KDM4E | |
| SCHEMBL21783477 | 0.74 | SCN1A (0.33) | SCN1ASCN5ASCN8ARIPK1KDM4E | |
| SCHEMBL21777156 | 0.65 | RIPK1 (0.40) | SCN1ASCN5ASCN8ARIPK1KDM4E | |
| SCHEMBL25488451 | 0.65 | RIPK1 (0.50) | RIPK1KDM4EALDH1A1 | |
| SCHEMBL19779344 | 0.65 | NOS3 (0.32) | — | |
| SCHEMBL20238171 | 0.62 | SCN8A (0.42) | SCN1ASCN5ASCN8ARIPK1KDM4E | |
| SCHEMBL14438269 | 0.62 | RIPK1 (0.53) | RIPK1KDM4EALDH1A1 | |
| SCHEMBL22349494 | 0.61 | HPGD (0.33) | KDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020047323-A1 | HETEROARYL-SUBSTITUTED SULFONAMIDE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2020-03-05 | — | — | WO | disclosed |