Norvaline

Norvaline

SCHEMBL2178341

CCC[C@H](N)C(=O)O.N[C@@H](CCC(=O)NCC(=O)O)C(=O)O

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.55
GSTK1 Q9Y2Q3 1/20 0.55
GLO1 Q04760 1/20 0.51
GRIK1 P39086 2/20 0.50
SLC1A3 P43003 2/20 0.50
SLC1A2 P43004 2/20 0.50
SLC1A1 P43005 2/20 0.50
GRIK2 Q13002 2/20 0.50
GRM8 O00222 1/20 0.50
GRM6 O15303 1/20 0.50
GRIN2D O15399 1/20 0.50
GRIN3B O60391 1/20 0.50
GSR P00390 1/20 0.50
CYP1A2 P05177 1/20 0.50
GRM5 P41594 1/20 0.50
GRIA1 P42261 1/20 0.50
GRIA2 P42262 1/20 0.50
GRIA3 P42263 1/20 0.50
GRIA4 P48058 1/20 0.50
GRIN1 Q05586 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1769059 0.91 PTGS1 (0.62) PTGS1GSTK1GLO1GRIK1SLC1A3
SCHEMBL1769055 0.91 PTGS1 (0.62) PTGS1GSTK1GLO1GRIK1SLC1A3
SCHEMBL2459448 0.91 PTGS1 (0.62) PTGS1GSTK1GLO1GRIK1SLC1A3
SCHEMBL6294950 0.88 PTGS1 (0.59) PTGS1GSTK1GLO1GRIK1SLC1A3
SCHEMBL2210613 0.88 PTGS1 (0.59) PTGS1GSTK1GLO1GRIK1SLC1A3
Cysteine SCHEMBL3317768 0.83 PTGS1 (0.67) PTGS1GSTK1GLO1GRIK1SLC1A3
SCHEMBL14510079 0.82 PTGS1 (0.73) PTGS1GSTK1GLO1GRIK1SLC1A3
SCHEMBL15443529 0.82 PTGS1 (0.73) PTGS1GSTK1GLO1GRIK1SLC1A3
Palmitoyl Glycine SCHEMBL2550958 0.81 FAAH (0.62) PTGS1GSTK1FAAHNOD1ALOX15
Palmitoyl Glycine SCHEMBL21383184 0.81 FAAH (0.62) PTGS1GSTK1FAAHNOD1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011081186-A1 FLAVOR-ENRICHING AGENT 味の素株式会社 (JP) 2011-07-07 WO disclosed