Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.62 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.62 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.59 |
| ▸ | GRM8 | O00222 | 2/20 | 0.59 |
| ▸ | GRM6 | O15303 | 2/20 | 0.59 |
| ▸ | GRM7 | Q14831 | 2/20 | 0.59 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.59 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.59 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.59 |
| ▸ | GSR | P00390 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.59 |
| ▸ | GRM5 | P41594 | 1/20 | 0.59 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.59 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.59 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.59 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.59 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.59 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.59 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1769055 | 1.00 | PTGS1 (0.62) | PTGS1GSTK1SLC1A1GRM8GRM6 | |
| SCHEMBL1769059 | 1.00 | PTGS1 (0.62) | PTGS1GSTK1SLC1A1GRM8GRM6 | |
| SCHEMBL2210613 | 0.96 | PTGS1 (0.59) | PTGS1GSTK1SLC1A1GRM8GRM6 | |
| SCHEMBL6294950 | 0.96 | PTGS1 (0.59) | PTGS1GSTK1SLC1A1GRM8GRM6 | |
| Cysteine SCHEMBL3317768 | 0.91 | PTGS1 (0.67) | PTGS1GSTK1SLC1A1GRM8GRM6 | |
| Norvaline SCHEMBL2178341 | 0.91 | PTGS1 (0.55) | PTGS1GSTK1SLC1A1GRM8GRM6 | |
| SCHEMBL31207012 | 0.86 | PTGS1 (0.49) | PTGS1GSTK1SLC1A1GRM8GRM6 | |
| SCHEMBL16203683 | 0.86 | PTGS1 (0.56) | PTGS1GSTK1SLC1A1GRM8GRM6 | |
| SCHEMBL10136169 | 0.85 | SLC1A1 (0.50) | PTGS1GSTK1SLC1A1GRM8GRM6 | |
| SCHEMBL9716241 | 0.85 | SLC1A1 (0.50) | PTGS1GSTK1SLC1A1GRM8GRM6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111323590-B | Application of anti-TIF 1 gamma-IgA and anti-TIF 1 gamma-IgG serving as combined diagnostic markers in lung cancer diagnosis | 福建省立医院 | 2022-04-22 | — | — | CN | claimed |
| US-20110244486-A1 | METHODS AND COMPOSITIONS FOR THE DIAGNOSIS AND TREATMENT OF DIABETES | PEREGO, CARLA (IT) | 2011-10-06 | — | — | US | claimed |
| EP-2366106-A2 | METHODS AND COMPOSITIONS FOR THE DIAGNOSIS AND TREATMENT OF DIABETES | Perego, Carla (IT) | 2011-09-21 | — | — | EP | claimed |
| WO-2010057647-A2 | METHODS AND COMPOSITIONS FOR THE DIAGNOSIS AND TREATMENT OF DIABETES | UNIVERSITA' DEGLI STUDI DI MILANO (IT) | 2010-05-27 | — | — | WO | claimed |
| EP-1586321-B1 | New use of glutamate antagonists for the treatment of cancer | IKONOMIDOU HRISSANTHI (DE) | 2008-12-10 | — | — | EP | claimed |
| US-7247610-B2 | Use of glutamate antagonists for the treatment of cancer | IKONOMIDOU HRISSANTHI | 2007-07-24 | — | — | US | claimed |
| EP-1586321-A1 | New use of glutamate antagonists for the treatment of cancer | Ikonomidou, Hrissanthi (DE) | 2005-10-19 | — | — | EP | claimed |
| US-20050054619-A1 | Use of glutamate antagonists for the treatment of cancer | IKONOMIDOU HRISSANTHI (DE) | 2005-03-10 | — | — | US | claimed |
| EP-1002535-A1 | New use of glutamate antagonists for the treatment of cancer | Ikonomidou, Hrissanthi (DE) | 2000-05-24 | — | — | EP | claimed |
| US-20250161238-A1 | NMDAR Antagonists Prevent Ageing and Aging-Associated Conditions and Diseases Through Increasing 20S Proteasome Activity | SAHIN FIKRET (TR) | 2025-05-22 | — | — | US | disclosed |
| CN-119586734-A | Dried egg prepared based on egg protein-sodium hyaluronate conjugate and preparation method thereof | 四川沈师傅食品有限公司 | 2025-03-11 | — | — | CN | disclosed |
| EP-4475953-A1 | NMDAR ANTAGONISTS PREVENT AGEING AND AGING-ASSOCIATED CONDITIONS AND DISEASES THROUGH INCREASING 20S PROTEASOME ACTIVITY | SAHIN, Fikret (TR) | 2024-12-18 | — | — | EP | disclosed |
| CN-119095622-A | NMDAR antagonists prevent aging and aging-related conditions and diseases by increasing 20S proteasome activity | 菲克雷特·萨欣 | 2024-12-06 | — | — | CN | disclosed |
| CN-117949519-A | Sample analysis method, solution for capillary electrophoresis, and kit for sample analysis | 爱科来株式会社 | 2024-04-30 | — | — | CN | disclosed |
| US-5196204-A | Spider toxins and methods for their use as blockers of calcium channels and amino acid receptor function | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 1993-03-23 | — | — | US | disclosed |
| US-5158976-A | CONTROLLING GLUTAMINE/GLUTAMATE RELATED NEURONAL INJURY | THE CHILDREN'S MEDICAL CENTER CORPORATION (US) | 1992-10-27 | — | — | US | disclosed |
| EP-0159889-B1 | 4-SUBSTITUTED PIPERAZINE-2-CARBOXYLIC ACIDS PROCESS AND PHARMACEUTICAL COMPOSITIONS | BTG INTERNATIONAL LIMITED (GB) | 1992-09-30 | — | — | EP | disclosed |
| US-5064657-A | Spider toxins and methods for their use as blockers of amino acid receptor function | UNIVERSITY OF UTAH (US) | 1991-11-12 | — | — | US | disclosed |
| US-4925664-A | Spider toxins and methods for their use as blockers of calcium channels and amino acid receptor function | UNIVERSITY OF UTAH (US) | 1990-05-15 | — | — | US | disclosed |
| US-4483853-A | ANTICONVULSANTS | COLLINS JAMES F | 1984-11-20 | — | — | US | disclosed |