Sugi Predict

Sugi Predict / Compounds / SCHEMBL1769055

SCHEMBL1769055

SCHEMBL1769055

N[C@@H](CCC(=O)NCC(=O)O)C(=O)O

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PTGS1 P23219 1/20 0.62
▸ GSTK1 Q9Y2Q3 1/20 0.62
▸ SLC1A1 P43005 2/20 0.59
▸ GRM8 O00222 2/20 0.59
▸ GRM6 O15303 2/20 0.59
▸ GRM7 Q14831 2/20 0.59
▸ GRM4 Q14833 2/20 0.59
▸ GRIN2D O15399 1/20 0.59
▸ GRIN3B O60391 1/20 0.59
▸ GSR P00390 1/20 0.59
▸ CYP1A2 P05177 1/20 0.59
▸ GRIK1 P39086 1/20 0.59
▸ GRM5 P41594 1/20 0.59
▸ GRIA1 P42261 1/20 0.59
▸ GRIA2 P42262 1/20 0.59
▸ GRIA3 P42263 1/20 0.59
▸ SLC1A3 P43003 1/20 0.59
▸ SLC1A2 P43004 1/20 0.59
▸ GRIA4 P48058 1/20 0.59
▸ GRIN1 Q05586 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2459448 1.00 PTGS1 (0.62) PTGS1GSTK1SLC1A1GRM8GRM6
SCHEMBL1769059 1.00 PTGS1 (0.62) PTGS1GSTK1SLC1A1GRM8GRM6
SCHEMBL2210613 0.96 PTGS1 (0.59) PTGS1GSTK1SLC1A1GRM8GRM6
SCHEMBL6294950 0.96 PTGS1 (0.59) PTGS1GSTK1SLC1A1GRM8GRM6
Cysteine SCHEMBL3317768 0.91 PTGS1 (0.67) PTGS1GSTK1SLC1A1GRM8GRM6
Norvaline SCHEMBL2178341 0.91 PTGS1 (0.55) PTGS1GSTK1SLC1A1GRM8GRM6
SCHEMBL31207012 0.86 PTGS1 (0.49) PTGS1GSTK1SLC1A1GRM8GRM6
SCHEMBL16203683 0.86 PTGS1 (0.56) PTGS1GSTK1SLC1A1GRM8GRM6
SCHEMBL10136169 0.85 SLC1A1 (0.50) PTGS1GSTK1SLC1A1GRM8GRM6
SCHEMBL9716241 0.85 SLC1A1 (0.50) PTGS1GSTK1SLC1A1GRM8GRM6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 187 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12584924-B2 Compositions and methods for diagnosing and treating chronic kidney disease SOCIETE DES PRODUITS NESTLE S.A. (CH) 2026-03-24 — — US claimed
US-12497644-B2 Subtilisin variants and their use Fresenius Kabi Ipsum S.R.L. (IT) 2025-12-16 — — US claimed
EP-4291647-B1 SUBTILISIN VARIANTS AND THEIR USE FRESENIUS KABI IPSUM S R L (IT) 2025-06-18 — — EP claimed
WO-2025069028-A1 FERMENTATION-DERIVED FLAVOR MATERIALS PRODUCED FROM GRAINS AND GRAIN PRODUCTS AND EDIBLE COMPOSITIONS CONTAINING SAME THE MEDITERRANEAN FOOD LAB LTD (IL) 2025-04-03 — — WO claimed
US-20250108119-A1 NOVEL STEROID PAYLOADS, STEROID LINKERS, ADCs CONTAINING AND USE THEREOF IMMUNEXT INC. 2025-04-03 — — US claimed
WO-2025069031-A1 FERMENTATION-DERIVED FLAVOR MATERIALS PRODUCED FROM OILSEEDS AND PLANTS AND EDIBLE COMPOSITIONS CONTAINING SAME THE MEDITERRANEAN FOOD LAB LTD (IL) 2025-04-03 — — WO claimed
CN-114269951-B Diagnostic method for aesthetic deterioration of skin 欧莱雅 2024-12-27 — — CN claimed
US-12050228-B2 Automated sample quality assessment METABOLON, INC. (US) 2024-07-30 — — US claimed
CN-118311265-A Metabolic molecular marker for differential diagnosis of diabetes after chronic pancreatitis 东南大学附属中大医院 2024-07-09 — — CN claimed
CN-117677302-A Peptide compounds for flavor modulation CJ第一制糖株式会社 2024-03-08 — — CN claimed
CN-114269951-A Diagnostic method for aesthetic deterioration of skin 欧莱雅 2022-04-01 — — CN claimed
EP-3796976-A1 COMPOSITIONS AND METHODS FOR DIAGNOSIS AND TREATMENT OF CONDITIONS RELATED TO THE QUALITY OF AGING AND LONGEVITY Epitracker, Inc. (US) 2021-03-31 — — EP claimed
US-20210088539-A1 AUTOMATED SAMPLE QUALITY ASSESSMENT METABOLON, INC. 2021-03-25 — — US claimed
US-10890592-B2 Automated sample quality assessment METABOLON, INC. (US) 2021-01-12 — — US claimed
WO-2020260355-A1 METHOD FOR DIAGNOSING ESTHETIC DEGRADATIONS OF SKIN L'OREAL (FR) 2020-12-30 — — WO claimed
US-20070099845-A1 Compounds for delivering amino acids or peptides with antioxidant activity into mitochondria and use thereof ROCHESTER, UNIVERSITY OF 2007-05-03 — — US claimed
EP-1691818-A4 COMPOUNDS FOR DELIVERING AMINO ACIDS OR PEPTIDES WITH ANTIOXIDANT ACTIVITY INTO MITOCHONDRIA AND USE THEREOF UNIV ROCHESTER (US) 2007-01-24 — — EP claimed
EP-1691818-A2 COMPOUNDS FOR DELIVERING AMINO ACIDS OR PEPTIDES WITH ANTIOXIDANT ACTIVITY INTO MITOCHONDRIA AND USE THEREOF University of Rochester (US) 2006-08-23 — — EP claimed
WO-2005051978-A2 COMPOUNDS FOR DELIVERING AMINO ACIDS OR PEPTIDES WITH ANTIOXIDANT ACTIVITY INTO MITOCHONDRIA AND USE THEREOF UNIVERSITY OF ROCHESTER (US) 2005-06-09 — — WO claimed
EP-0266905-A1 Reagents for assay of gamma-glutamyl-transpeptidase UNITIKA LTD. (JP) 1988-05-11 — — EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070099845-A1 Compounds for delivering amino acids or peptides with antioxidant activity into mitochondria and use thereof TXN2, GLS, PDF PTGS1 640/4885GSTK1 227/4885SLC1A1 675/4885
US-12584924-B2 Compositions and methods for diagnosing and treating chronic kidney disease GLS, AADAT, FGF23 PTGS1 2333/4885GSTK1 3525/4885SLC1A1 87/4885
US-20250108119-A1 NOVEL STEROID PAYLOADS, STEROID LINKERS, ADCs CONTAINING AND USE THEREOF FCGR2A, FCER2, FCGR1A PTGS1 734/4885GSTK1 377/4885SLC1A1 1685/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.