Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TYMP | P19971 | 1/20 | 0.33 |
| ▸ | PGK1 | P00558 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | GLP1R | P43220 | 1/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4188467 | 0.72 | ALDH1A1 (0.37) | KMT2AGLP1RHSP90AA1HSP90AB1 | |
| SCHEMBL30313634 | 0.72 | ALDH1A1 (0.37) | KMT2AGLP1RHSP90AA1HSP90AB1 | |
| SCHEMBL18075327 | 0.70 | PDE2A (0.44) | KMT2AKDM4ETYMP | |
| SCHEMBL18075325 | 0.70 | PDE2A (0.44) | KMT2AKDM4ETYMP | |
| SCHEMBL4797238 | 0.64 | ALDH1A1 (0.43) | KMT2AKDM4EGLP1RHSP90AA1HSP90AB1 | |
| SCHEMBL10322856 | 0.63 | ALDH1A1 (0.44) | KMT2AKDM4ETYMPHTTSMN1; SMN2 | |
| SCHEMBL14416284 | 0.63 | ALDH1A1 (0.44) | KMT2AKDM4ETYMPHTTSMN1; SMN2 | |
| SCHEMBL257115 | 0.63 | ALDH1A1 (0.44) | KMT2AKDM4ETYMPHTTSMN1; SMN2 | |
| SCHEMBL25249144 | 0.62 | MAPKAPK2 (0.31) | — | |
| SCHEMBL25291852 | 0.62 | MAPKAPK2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020081154-A1 | INHIBITORS OF ανβ6 INTEGRIN | MORPHIC THERAPEUTIC, INC. (US) | 2020-04-23 | — | — | WO | disclosed |
| WO-2020047208-A1 | INHIBITORS OF (ALPHA-V)(BETA-6) INTEGRIN | MORPHIC THERAPEUTIC, INC. (US) | 2020-03-05 | — | — | WO | disclosed |