SCHEMBL30313634

SCHEMBL30313634

Nc1nc(Cl)cc(Cl)c1C=O

nearest known ligand 0.37

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
TDP1 Q9NUW8 1/20 0.37
GLP1R P43220 1/20 0.34
LMNA P02545 1/20 0.32
HSP90AB1 P08238 3/20 0.31
HSP90AA1 P07900 2/20 0.31
CYP2D6 P10635 1/20 0.30
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4188467 1.00 ALDH1A1 (0.37) ALDH1A1MEN1KMT2ATDP1GLP1R
SCHEMBL7699406 0.78 ALDH1A1 (0.39) ALDH1A1MEN1KMT2ATDP1LMNA
SCHEMBL29950600 0.78 ALDH1A1 (0.39) ALDH1A1MEN1KMT2ATDP1LMNA
SCHEMBL30592272 0.75 ALDH1A1 (0.37) ALDH1A1MEN1KMT2ATDP1LMNA
SCHEMBL16463746 0.75 ALDH1A1 (0.37) ALDH1A1MEN1KMT2ATDP1LMNA
SCHEMBL27776286 0.73 KDM4E (0.44) ALDH1A1MEN1KMT2ALMNAHSP90AB1
SCHEMBL21783716 0.72 KMT2A (0.34) KMT2AGLP1RHSP90AB1HSP90AA1
SCHEMBL27631288 0.71 LMNA (0.39) ALDH1A1MEN1KMT2ATDP1GLP1R
SCHEMBL29951323 0.71 TDP1 (0.40) ALDH1A1MEN1KMT2ATDP1LMNA
SCHEMBL16857047 0.71 TDP1 (0.40) ALDH1A1MEN1KMT2ATDP1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4720057-A2 COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF Oncopia Therapeutics, Inc. D/B/A SK Life Science Labs (US) 2026-04-08 EP disclosed
US-20250114345-A1 COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF ONCOPIA THERAPEUTICS, INC. D/B/A/ SK LIFE SCIENCE LABS 2025-04-10 US disclosed
WO-2025049994-A1 COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF ONCOPIA THERAPEUTICS, INC. D/B/A SK LIFE SCIENCE LABS (US) 2025-03-06 WO disclosed
WO-2024249888-A2 COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF ONCOPIA THERAPEUTICS, INC. D/B/A SK LIFE SCIENCE LABS (US) 2024-12-05 WO disclosed
CN-117597333-A Heterocyclic compounds as receptor 2-triggering agonists expressed on myeloid cells and methods of use 维吉尔神经科学股份有限公司 2024-02-23 CN disclosed
CN-115867284-A Heterocyclic compounds as trigger receptor 2 agonists expressed on myeloid cells and methods of use 安进公司 2023-03-28 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250114345-A1 COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF EP300, CREBBP, HDAC1 ALDH1A1 1582/4885MEN1 2485/4885KMT2A 689/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.