Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.65 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.65 |
| ▸ | TUBB | P07437 | 1/20 | 0.65 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.65 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.65 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.65 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.65 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.65 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.65 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.65 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.65 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.65 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.65 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.65 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.65 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.54 |
| ▸ | HPGD | P15428 | 7/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Confusameline SCHEMBL30525089 | 1.00 | KDM4E (0.65) | KDM4ETUBB4ATUBBTUBA3CTUBA1B | |
| Evolitrine SCHEMBL30105705 | 0.84 | KDM4E (0.67) | KDM4ETUBB4ATUBBTUBA3CTUBA1B | |
| Kokusaginine SCHEMBL23870280 | 0.79 | KDM4E (1.00) | KDM4ETUBB4ATUBBTUBA3CTUBA1B | |
| Kokusaginine SCHEMBL30609976 | 0.79 | KDM4E (1.00) | KDM4ETUBB4ATUBBTUBA3CTUBA1B | |
| Dictamnine SCHEMBL1760700 | 0.78 | POLB (0.65) | KDM4ETUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL29827080 | 0.75 | ALDH1A1 (0.71) | KDM4ETUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL15263337 | 0.75 | ALDH1A1 (0.71) | KDM4ETUBB4ATUBBTUBA3CTUBA1B | |
| Maculine SCHEMBL29461401 | 0.74 | KDM4E (0.66) | KDM4ETUBB4ATUBBTUBA3CTUBA1B | |
| Maculine SCHEMBL30361505 | 0.74 | KDM4E (0.66) | KDM4ETUBB4ATUBBTUBA3CTUBA1B | |
| Robustine SCHEMBL31419857 | 0.71 | KDM4E (0.72) | KDM4ETUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3847163-B1 | BIOACTIVE COMPOUND | HARDIE HEALTH LTD (NZ) | 2023-07-19 | — | — | EP | disclosed |
| US-20210332023-A1 | BIOACTIVE COMPOUND | HARDIE HEALTH LIMITED (NZ) | 2021-10-28 | — | — | US | disclosed |
| WO-2020044245-A1 | BIOACTIVE COMPOUND | HARDIE HEALTH LIMITED (NZ) | 2020-03-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210332023-A1 | BIOACTIVE COMPOUND | MLX, MELK, BMX | KDM4E 2489/4885TUBB4A 1616/4885TUBB 1767/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.