Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | MGAM | O43451 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SI | P14410 | 1/20 | 0.38 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23643036 | 0.82 | MGAM (0.42) | LTA4HKMT2APOLBL3MBTL1CYP1A2 | |
| SCHEMBL20937509 | 0.81 | LTA4H (0.52) | LTA4HKMT2APOLBCYP1A2MGAM | |
| SCHEMBL20937053 | 0.79 | LTA4H (0.54) | LTA4HKMT2APOLBCYP1A2MGAM | |
| SCHEMBL1327984 | 0.79 | CYP1A2 (0.55) | LTA4HPOLBCYP1A2MGAMGAA | |
| Hydrochloric Acid SCHEMBL1274072 | 0.79 | LTA4H (0.54) | LTA4HKMT2APOLBCYP1A2MGAM | |
| SCHEMBL4464939 | 0.79 | GAA (0.59) | LTA4HKMT2APOLBL3MBTL1CYP1A2 | |
| SCHEMBL14241233 | 0.79 | L3MBTL1 (0.42) | LTA4HKMT2APOLBL3MBTL1CYP1A2 | |
| SCHEMBL5011369 | 0.78 | LTA4H (0.50) | LTA4HKMT2APOLBCYP1A2MGAM | |
| SCHEMBL16213690 | 0.78 | L3MBTL1 (0.41) | LTA4HKMT2APOLBL3MBTL1CYP1A2 | |
| Hydrochloric Acid SCHEMBL11851530 | 0.77 | GAA (0.56) | LTA4HKMT2APOLBL3MBTL1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020047186-A1 | SMALL MOLECULE STIMULATORS OF STEROID RECEPTOR COACTIVATOR-3 AND METHODS OF THEIR USE AS CARDIOPROTECTIVE AND/OR VASCULAR REGENERATIVE AGENTS | BAYLOR COLLEGE OF MEDICINE (US) | 2020-03-05 | — | — | WO | disclosed |