Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 4/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | MGAM | O43451 | 1/20 | 0.48 |
| ▸ | SI | P14410 | 1/20 | 0.48 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | DGKA | P23743 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4439462 | 0.94 | LTA4H (0.51) | LTA4HCYP1A2GAAMGAMSI | |
| SCHEMBL16838958 | 0.92 | LTA4H (0.50) | LTA4HCYP1A2GAAMGAMSI | |
| SCHEMBL26241128 | 0.92 | LTA4H (0.50) | LTA4HCYP1A2GAAMGAMSI | |
| SCHEMBL28364724 | 0.92 | LTA4H (0.50) | LTA4HCYP1A2GAAMGAMSI | |
| SCHEMBL5123883 | 0.92 | LTA4H (0.50) | LTA4HCYP1A2GAAMGAMSI | |
| SCHEMBL11194462 | 0.92 | LTA4H (0.50) | LTA4HCYP1A2GAAMGAMSI | |
| SCHEMBL20937509 | 0.92 | LTA4H (0.52) | LTA4HCYP1A2GAAMGAMSI | |
| SCHEMBL7518611 | 0.90 | DGKA (0.57) | LTA4HCYP1A2GAAMGAMSI | |
| Hydrochloric Acid SCHEMBL1274072 | 0.90 | LTA4H (0.54) | LTA4HCYP1A2GAAMGAMSI | |
| SCHEMBL20937053 | 0.90 | LTA4H (0.54) | LTA4HCYP1A2GAAMGAMSI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12121604-B2 | Composition comprising hydroxylated diphenylmethane derivatives | L'OREAL (FR) | 2024-10-22 | — | — | US | claimed |
| CN-117338637-A | Compositions comprising hydroxylated diphenylmethane derivatives | 莱雅公司 | 2024-01-05 | — | — | CN | claimed |
| CN-113461560-A | Repellent, product, preparation method and application thereof | 中国人民解放军军事科学院军事医学研究院 | 2021-10-01 | — | — | CN | claimed |
| EP-3386469-A1 | COMPOSITION COMPRISING HYDROXYLATED DIPHENYLMETHANE DERIVATIVES | L'OREAL (FR) | 2018-10-17 | — | — | EP | claimed |
| CN-108601713-A | The composition of oil-in-water emulsion form | 莱雅公司 | 2018-09-28 | — | — | CN | claimed |
| US-20180263875-A1 | COMPOSITION COMPRISING HYDROXYLATED DIPHENYLMETHANE DERIVATIVES | L'OREAL (FR) | 2018-09-20 | — | — | US | claimed |
| CN-108289810-A | Composition comprising a hydroxylated diphenylmethane derivative | 莱雅公司 | 2018-07-17 | — | — | CN | claimed |
| WO-2017096583-A1 | COMPOSITION COMPRISING HYDROXYLATED DIPHENYLMETHANE DERIVATIVES | L'OREAL (FR) | 2017-06-15 | — | — | WO | claimed |
| EP-0449989-A1 | 6,7 DIHYDROPYRROLO 3,4-c] PYRIDO 2,3-d] PYRIMIDINE DERIVATIVES | Sloan-Kettering Institute For Cancer Research (US) | 1991-10-09 | — | — | EP | claimed |
| WO-1990007496-A1 | 6,7 DIHYDROPYRROLO[3,4-c] PYRIDO[2,3-d] PYRIMIDINE DERIVATIVES | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1990-07-12 | — | — | WO | claimed |
| US-12121604-B2 | Composition comprising hydroxylated diphenylmethane derivatives | L'OREAL (FR) | 2024-10-22 | — | — | US | disclosed |
| CN-117338637-A | Compositions comprising hydroxylated diphenylmethane derivatives | 莱雅公司 | 2024-01-05 | — | — | CN | disclosed |
| CN-113461560-B | Repellent, and product, preparation method and application thereof | 中国人民解放军军事科学院军事医学研究院 | 2023-08-08 | — | — | CN | disclosed |
| CN-113461560-A | Repellent, product, preparation method and application thereof | 中国人民解放军军事科学院军事医学研究院 | 2021-10-01 | — | — | CN | disclosed |
| EP-3386469-A1 | COMPOSITION COMPRISING HYDROXYLATED DIPHENYLMETHANE DERIVATIVES | L'OREAL (FR) | 2018-10-17 | — | — | EP | disclosed |
| EP-0441349-A1 | Pyrroloazepine derivatives | SUNTORY LIMITED (JP) | 1991-08-14 | — | — | EP | disclosed |
| WO-1990007496-A1 | 6,7 DIHYDROPYRROLO[3,4-c] PYRIDO[2,3-d] PYRIMIDINE DERIVATIVES | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1990-07-12 | — | — | WO | disclosed |
| US-4925939-A | 6,7-dihydropyrrol[3,4-c]pyrido[2,3-d]pyrimidine derivatives | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1990-05-15 | — | — | US | disclosed |
| US-4421693-A | INSECTICIDES, MITICIDES OR NEMATOCIDES | OTSUKA CHEMICAL CO., LTD. (JP) | 1983-12-20 | — | — | US | disclosed |
| US-4413005-A | 2,3-DIHYDRO-2,2-DIMETHYLBENZOFURAN-7-YL DERIVATIVES | OTSUKA KAGAKU YAKUHIN KABUSHIKI KAISHA (JP) | 1983-11-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180263875-A1 | COMPOSITION COMPRISING HYDROXYLATED DIPHENYLMETHANE DERIVATIVES | DEGS1, ALOX5, ALOX12 | LTA4H 544/4885CYP1A2 214/4885GAA 4863/4885 |
| US-12121604-B2 | Composition comprising hydroxylated diphenylmethane derivatives | DEGS1, ALOX5, ALOX12 | LTA4H 544/4885CYP1A2 214/4885GAA 4863/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.