Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | DAO | P14920 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CES1 | P23141 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.43 |
| ▸ | MITF | O75030 | 2/20 | 0.43 |
| ▸ | OXTR | P30559 | 1/20 | 0.43 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5772644 | 0.74 | ERCC5 (0.44) | GSK3BMAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL21784396 | 0.74 | NPC1 (0.73) | GSK3BMAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL21784395 | 0.74 | CYP3A4 (0.53) | MAPTKMT2AMEN1SMN1; SMN2CES1 | |
| SCHEMBL21784398 | 0.72 | MEN1 (0.50) | MAPTKMT2AMEN1SMN1; SMN2CES1 | |
| SCHEMBL31415977 | 0.71 | KMT2A (0.50) | MAPTDAOKMT2AMEN1SMN1; SMN2 | |
| Benzene SCHEMBL29173830 | 0.70 | MAPT (0.46) | GSK3BMAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL6203313 | 0.69 | GSK3B (0.59) | GSK3BMAPTDAOKMT2AMEN1 | |
| SCHEMBL22805019 | 0.69 | PLOD2 (0.60) | MAPTKMT2AMEN1SMN1; SMN2CES1 | |
| SCHEMBL14624168 | 0.69 | GSK3B (0.63) | GSK3BMAPTDAOKMT2AMEN1 | |
| SCHEMBL23959941 | 0.68 | GSK3B (0.58) | GSK3BMAPTDAOKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020044213-A1 | DIPHENYLAMINO-METHYLENE MALONONITRILE BASED COMPOUNDS AS FLUORESCENCE PROBES | UNIVERSITY OF HYDERABAD (IN) | 2020-03-05 | — | — | WO | disclosed |