SCHEMBL2178556

SCHEMBL2178556

CNC(=O)OSCC(N)=O

nearest known ligand 0.33

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 1/20 0.33
CHRM4 P08173 1/20 0.33
CHRM5 P08912 1/20 0.33
CYP2D6 P10635 1/20 0.33
CHRM1 P11229 1/20 0.33
CHRNB2 P17787 1/20 0.33
NFKB1 P19838 1/20 0.33
CHRM3 P20309 1/20 0.33
MAPK1 P28482 1/20 0.33
CHRNA7 P36544 1/20 0.33
CHRNA4 P43681 1/20 0.33
TDP1 Q9NUW8 1/20 0.32
LMNA P02545 1/20 0.32
APEX1 P27695 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
EPHX1 P07099 1/20 0.32
MAPT P10636 2/20 0.31
ALDH1A1 P00352 1/20 0.31
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6607573 0.71 ALDH1A1 (0.35) ALDH1A1
Bromide SCHEMBL8502372 0.70
SCHEMBL11060245 0.69 TDP1 (0.34) TDP1ALDH1A1HSD17B10
SCHEMBL11060249 0.69 TDP1 (0.34) TDP1ALDH1A1HSD17B10
SCHEMBL3085920 0.68
SCHEMBL10592789 0.68
SCHEMBL11094903 0.67 TDP1 (0.33) TDP1
SCHEMBL28818267 0.67
SCHEMBL19663841 0.67
SCHEMBL13324711 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021041278-A2 COMPOSITIONS AND METHODS RELATING TO INSECTICIDES UNIVERSITY OF FLORIDA RESEARCH FOUNDATION (US) 2021-03-04 WO disclosed
WO-2020198414-A1 COMPOSITIONS AND METHODS RELATING TO INSECTICIDES UNIVERSITY OF FLORIDA RESEARCH FOUNDATION (US) 2020-10-01 WO disclosed
EP-3709804-A1 PESTICIDAL COMPOSITIONS AND RELATED METHODS CJB Applied Technologies, LLC (US) 2020-09-23 EP disclosed
US-20140162906-A1 Pesticide Biomarker NAGY JON OWEN (US) 2014-06-12 US disclosed
US-20110166043-A1 BIOMARKER DETECTION-2 ATERIS TECHNOLOGIES, LLC 2011-07-07 US disclosed
US-20100041077-A1 PESTICIDE BIOMARKER ATERIS TECHNOLOGIES, LLC 2010-02-18 US disclosed
EP-2106257-A2 COMPOSITIONS FOR PROVIDING COLOR TO ANIMATE OBJECTS AND RELATED METHODS PPG Industries Ohio, Inc. (US) 2009-10-07 EP disclosed
EP-1989209-A2 ORGANIC COMPOUNDS Novartis AG (CH) 2008-11-12 EP disclosed
WO-2008091916-A2 COMPOSITIONS FOR PROVIDING COLOR TO ANIMATE OBJECTS AND RELATED METHODS PPG INDUSTRIES OHIO, INC. (US) 2008-07-31 WO disclosed
EP-1945611-A1 N- (HETERO) ARYL INDOLE DERIVATIVES AS PESTICIDES Novartis Pharma AG (CH) 2008-07-23 EP disclosed
WO-2001036372-A1 ORGANIC COMPOUNDS AND THEIR USE IN THE CONTROL OF ECTOPARASITES NOVARTIS AG (CH) 2001-05-25 WO disclosed
WO-2001036415-A1 PESTICIDAL AMINOHETEROCYCLAMIDE COMPOUNDS NOVARTIS AG (CH) 2001-05-25 WO disclosed
WO-2001015684-A2 ANTIMYCOTIC DRUG NOVARTIS AG (CH) 2001-03-08 WO disclosed
WO-2000073310-A1 4-SUBSTITUTED MILBEMYCIN DERIVATIVES NOVARTIS AG (CH) 2000-12-07 WO disclosed
WO-2000058291-A1 PESTICIDAL ENANTIOMER-PURE 2,4-DISUBSTITUTED OXAZOLINES NOVARTIS AG (CH) 2000-10-05 WO disclosed
WO-2000042047-A1 4-PHENOXYMETHYL-SUBSTITUTED MILBEMYCINS NOVARTIS AG (CH) 2000-07-20 WO disclosed
EP-0824314-A1 EFFICACY ENHANCER FOR AGRICULTURAL CHEMICALS AND AGRICULTURAL CHEMICAL COMPOSITIONS Kao Corporation (JP) 1998-02-25 EP disclosed
WO-1997031527-A1 EFFICACY ENHANCER FOR AGRICULTURAL CHEMICALS AND AGRICULTURAL CHEMICAL COMPOSITIONS KAO CORPORATION (JP) 1997-09-04 WO disclosed
US-5093358-A MACROCYCLIC PLANT ACARICIDES CIBA-GEIGY CORP. (US) 1992-03-03 US disclosed
US-4315026-A INSECTICIDES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1982-02-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110166043-A1 BIOMARKER DETECTION-2 CPB2, NAALAD2, PRSS2 CHRM2 241/4885CHRM4 381/4885CHRM5 502/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.