Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.59 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.59 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | BAX | Q07812 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.38 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.38 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.38 |
| ▸ | P4HB | P07237 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22003012 | 1.00 | ESR1 (0.59) | ESR1ESR2ADORA3LTA4HNR1H2 | |
| SCHEMBL21785664 | 1.00 | ESR1 (0.59) | ESR1ESR2ADORA3LTA4HNR1H2 | |
| SCHEMBL22003010 | 1.00 | ESR1 (0.59) | ESR1ESR2ADORA3LTA4HNR1H2 | |
| SCHEMBL11949464 | 0.97 | ESR1 (0.59) | ESR1ESR2ADORA3LTA4HNR1H2 | |
| SCHEMBL22003011 | 0.94 | ADORA3 (0.50) | ESR1ESR2ADORA3FAAHKDM4E | |
| SCHEMBL22003009 | 0.94 | ESR1 (0.67) | ESR1ESR2ADORA3KDM4EALDH1A1 | |
| SCHEMBL16395122 | 0.94 | ADORA3 (0.50) | ESR1ESR2ADORA3FAAHKDM4E | |
| SCHEMBL21785618 | 0.94 | ESR1 (0.67) | ESR1ESR2ADORA3KDM4EALDH1A1 | |
| SCHEMBL21785675 | 0.94 | ADORA3 (0.50) | ESR1ESR2ADORA3FAAHKDM4E | |
| SCHEMBL23968910 | 0.87 | ESR2 (0.57) | ESR1ESR2ADORA3LTA4HFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200071461-A1 | AROMATIC POLYCARBONATE OLIGOMER SOLID | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2020-03-05 | — | — | US | disclosed |