Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.67 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.67 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.41 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.41 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22003009 | 1.00 | ESR1 (0.67) | ESR1ESR2ADORA3ALDH1A1L3MBTL1 | |
| SCHEMBL22003012 | 0.94 | ESR1 (0.59) | ESR1ESR2ADORA3ALDH1A1L3MBTL1 | |
| SCHEMBL11949464 | 0.94 | ESR1 (0.59) | ESR1ESR2ADORA3ALDH1A1L3MBTL1 | |
| SCHEMBL21785601 | 0.94 | ESR1 (0.59) | ESR1ESR2ADORA3ALDH1A1L3MBTL1 | |
| SCHEMBL21785664 | 0.94 | ESR1 (0.59) | ESR1ESR2ADORA3ALDH1A1L3MBTL1 | |
| SCHEMBL22003010 | 0.94 | ESR1 (0.59) | ESR1ESR2ADORA3ALDH1A1L3MBTL1 | |
| SCHEMBL23968910 | 0.93 | ESR2 (0.57) | ESR1ESR2ADORA3ALDH1A1MAPT | |
| SCHEMBL21142158 | 0.89 | ESR1 (0.65) | ESR1ESR2ADORA3ALDH1A1L3MBTL1 | |
| SCHEMBL7187586 | 0.89 | ESR1 (0.65) | ESR1ESR2ADORA3ALDH1A1L3MBTL1 | |
| SCHEMBL8862756 | 0.89 | ESR1 (0.65) | ESR1ESR2ADORA3ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200071461-A1 | AROMATIC POLYCARBONATE OLIGOMER SOLID | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2020-03-05 | — | — | US | disclosed |