SCHEMBL23968910

SCHEMBL23968910

COc1ccc(C2(c3ccc(OC(=O)Oc4ccc(C5(c6ccc(O)cc6)CCCCC5)cc4)cc3)CCCCC2)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 3/20 0.57
ESR1 P03372 2/20 0.57
ADORA3 P0DMS8 1/20 0.45
BACE1 P56817 2/20 0.43
SLC6A4 P31645 2/20 0.42
SLC6A3 Q01959 2/20 0.42
GRIN1 Q05586 1/20 0.42
GRIN2A Q12879 1/20 0.42
GRIN2B Q13224 1/20 0.42
LTA4H P09960 1/20 0.42
CYP3A4 P08684 1/20 0.41
CYP2C19 P33261 1/20 0.41
GAA P10253 1/20 0.41
PKM P14618 1/20 0.41
KDM4E B2RXH2 2/20 0.40
MAPT P10636 2/20 0.40
CYP2C9 P11712 1/20 0.40
HPGD P15428 1/20 0.40
KMT2A Q03164 1/20 0.40
FAAH O00519 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21785618 0.93 ESR1 (0.67) ESR2ESR1ADORA3BACE1GAA
SCHEMBL22003009 0.93 ESR1 (0.67) ESR2ESR1ADORA3BACE1GAA
SCHEMBL8760127 0.89 ESR2 (0.71) ESR2ESR1ADORA3BACE1SLC6A4
SCHEMBL14877709 0.89 KDM4E (0.47) ESR2ESR1ADORA3BACE1SLC6A4
SCHEMBL12221853 0.89 FAAH (0.48) ADORA3BACE1SLC6A4SLC6A3GRIN1
SCHEMBL19194913 0.89 KMT2A (0.51) ESR2ESR1ADORA3BACE1SLC6A4
SCHEMBL13583422 0.88 SLC6A4 (0.49) ESR2ESR1ADORA3BACE1SLC6A4
SCHEMBL22003010 0.87 ESR1 (0.59) ESR2ESR1ADORA3LTA4HGAA
SCHEMBL22003012 0.87 ESR1 (0.59) ESR2ESR1ADORA3LTA4HGAA
SCHEMBL21785601 0.87 ESR1 (0.59) ESR2ESR1ADORA3LTA4HGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3388467-B1 AROMATIC POLYCARBONATE OLIGOMER SOLID HONSHU CHEMICAL IND (JP) 2021-11-03 EP disclosed