SCHEMBL7187586

SCHEMBL7187586

O=C(O)Oc1ccc(C2(c3ccc(O)cc3)CCCCC2)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 4/20 0.65
ESR2 Q92731 4/20 0.65
ADORA3 P0DMS8 1/20 0.49
ALDH1A1 P00352 3/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
MAPT P10636 2/20 0.41
GAA P10253 2/20 0.41
XBP1 P17861 1/20 0.41
PSMB1 P20618 1/20 0.40
PSMB5 P28074 1/20 0.40
PSMB2 P49721 1/20 0.40
ELANE P08246 2/20 0.38
PPARA Q07869 1/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
TSHR P16473 1/20 0.36
HTT P42858 2/20 0.36
LMNA P02545 1/20 0.36
ALOX12 P18054 1/20 0.36
POLB P06746 3/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21142158 1.00 ESR1 (0.65) ESR1ESR2ADORA3ALDH1A1L3MBTL1
SCHEMBL8862756 1.00 ESR1 (0.65) ESR1ESR2ADORA3ALDH1A1L3MBTL1
SCHEMBL12521524 0.89 ESR1 (0.62) ESR1ESR2ADORA3ALDH1A1L3MBTL1
SCHEMBL13983792 0.89 ADORA3 (0.50) ESR1ESR2ADORA3ALDH1A1L3MBTL1
SCHEMBL21785618 0.89 ESR1 (0.67) ESR1ESR2ADORA3ALDH1A1L3MBTL1
SCHEMBL22003009 0.89 ESR1 (0.67) ESR1ESR2ADORA3ALDH1A1L3MBTL1
SCHEMBL21785601 0.86 ESR1 (0.59) ESR1ESR2ADORA3ALDH1A1L3MBTL1
SCHEMBL22003010 0.86 ESR1 (0.59) ESR1ESR2ADORA3ALDH1A1L3MBTL1
SCHEMBL22003012 0.86 ESR1 (0.59) ESR1ESR2ADORA3ALDH1A1L3MBTL1
SCHEMBL21785664 0.86 ESR1 (0.59) ESR1ESR2ADORA3ALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5698665-A Polycarbonate processes with supercritical carbon dioxide XEROX CORPORATION (US) 1997-12-16 US claimed
US-6573017-B2 Electroconductive substrate overcoated with photosensitive layer; sensitivity, wear resistance and ozone resistance KYOCERA MITA CORPORATION (JP) 2003-06-03 US disclosed
US-20020119385-A1 Single-layer type electrophotosensitive material KYOCERA MITA CORPORATION (JP) 2002-08-29 US disclosed
US-6096464-A CHARGE TRANSPORT LAYER INCLUDES A CHARGE TRANSPORT MATERIAL AND A ROTAXANE MATERIAL; PHOTORECEPTORS HAVE EXCELLENT XEROGRAPHIC PROPERTIES SUCH AS HIGH PHOTOSENSITIVITY AND LOW RESIDUAL VOLTAGE AND IMPROVED ABRASION RESISTANCE XEROX CORPORATION (US) 2000-08-01 US disclosed
US-5998077-A Coated carrier XEROX CORPORATION (US) 1999-12-07 US disclosed
US-5698665-A Polycarbonate processes with supercritical carbon dioxide XEROX CORPORATION (US) 1997-12-16 US disclosed
US-5300392-A Imaging member with polycarbonate obtained from cyclic oligomers XEROX CORPORATION (US) 1994-04-05 US disclosed
US-5227449-A Polydiphenylsiloxane-Carbonate Block Polymers XEROX CORPORATION (US) 1993-07-13 US disclosed
US-5166021-A Multilayer imaging member with charge generating and charge transport layers XEROX CORPORATION (US) 1992-11-24 US disclosed
US-5080987-A Photoconductive imaging members with polycarbonate binders XEROX CORPORATION (US) 1992-01-14 US disclosed