Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | PER2 | O15055 | 2/20 | 0.43 |
| ▸ | CRY2 | Q49AN0 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19547094 | 0.83 | RAB9A (0.50) | RAB9ASMN1; SMN2PER2CRY2GAA | |
| SCHEMBL21777816 | 0.80 | F10 (0.44) | RAB9ASMN1; SMN2L3MBTL1HSD11B1USP2 | |
| SCHEMBL14411952 | 0.79 | LMNA (0.40) | RAB9ASMN1; SMN2L3MBTL1HSD11B1USP2 | |
| SCHEMBL8790936 | 0.79 | SMN1; SMN2 (0.81) | RAB9ASMN1; SMN2GAAL3MBTL1HSD11B1 | |
| SCHEMBL12561298 | 0.77 | LMNA (0.44) | USP2LMNA | |
| SCHEMBL12561299 | 0.77 | LMNA (0.44) | USP2LMNA | |
| SCHEMBL12411801 | 0.77 | LMNA (0.44) | USP2LMNA | |
| SCHEMBL12847990 | 0.75 | LMNA (0.42) | USP2LMNA | |
| SCHEMBL12376641 | 0.75 | LMNA (0.42) | USP2LMNA | |
| SCHEMBL13342365 | 0.75 | LMNA (0.42) | USP2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020047184-A1 | PYRAZOLO[3,4-b]PYRIDINE COMPOUNDS AS INHIBITORS OF TAM AND MET KINASES | ARRAY BIOPHARMA INC. (US) | 2020-03-05 | — | — | WO | disclosed |