Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.81 |
| ▸ | RAB9A | P51151 | 2/20 | 0.81 |
| ▸ | GAA | P10253 | 2/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | NSD2 | O96028 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.41 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12584934 | 0.82 | SMN1; SMN2 (0.84) | SMN1; SMN2RAB9AGAAL3MBTL1POLB | |
| SCHEMBL1208088 | 0.82 | SMN1; SMN2 (0.84) | SMN1; SMN2RAB9AGAAL3MBTL1POLB | |
| SCHEMBL13932030 | 0.81 | SMN1; SMN2 (0.81) | SMN1; SMN2RAB9AGAAL3MBTL1POLB | |
| SCHEMBL8791216 | 0.81 | SMN1; SMN2 (0.81) | SMN1; SMN2RAB9AGAAL3MBTL1POLB | |
| SCHEMBL21786014 | 0.79 | RAB9A (0.50) | SMN1; SMN2RAB9AGAAL3MBTL1POLB | |
| SCHEMBL8299157 | 0.78 | GAA (1.00) | SMN1; SMN2RAB9AGAAL3MBTL1POLB | |
| SCHEMBL8791412 | 0.78 | RAB9A (0.75) | SMN1; SMN2RAB9AGAAL3MBTL1POLB | |
| SCHEMBL14003534 | 0.77 | L3MBTL1 (1.00) | SMN1; SMN2RAB9AGAAL3MBTL1POLB | |
| SCHEMBL1208101 | 0.77 | SMN1; SMN2 (0.72) | SMN1; SMN2RAB9AGAAL3MBTL1POLB | |
| SCHEMBL9340652 | 0.75 | RAB9A (0.50) | SMN1; SMN2RAB9AGAAL3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0800516-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS HAVING SUBSTITUTED (b)-AMINO ACID RESIDUES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | NIPPON STEEL CORPORATION (JP) | 1997-10-15 | — | — | EP | disclosed |