SCHEMBL21786071

SCHEMBL21786071

CC(C)(C)OC(=O)N1CCN(CC2CCN(c3ccc(N)cc3F)CC2)CC1

nearest known ligand 0.46

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 1/20 0.44
GPR119 Q8TDV5 6/20 0.43
NR1H2 P55055 1/20 0.43
DPP4 P27487 1/20 0.43
ALDH1A1 P00352 2/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
MAPT P10636 2/20 0.41
USP30 Q70CQ3 1/20 0.41
NPC1 O15118 1/20 0.41
MAPK1 P28482 1/20 0.41
HTT P42858 1/20 0.41
RAB9A P51151 1/20 0.41
BACE1 P56817 1/20 0.41
HRH3 Q9Y5N1 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27162423 0.96 GPR119 (0.46) CNR1GPR119NR1H2DPP4ALDH1A1
SCHEMBL30207450 0.89 GPR119 (0.51) GPR119NR1H2DPP4SMN1; SMN2
SCHEMBL31333808 0.89 GPR119 (0.48) GPR119NR1H2DPP4SMN1; SMN2
SCHEMBL31640106 0.88 DPP4 (0.44) CNR1GPR119DPP4BACE1
SCHEMBL29059671 0.87 ACHE (0.51) CNR1GPR119NR1H2ALDH1A1L3MBTL1
SCHEMBL31701731 0.86 GPR119 (0.44) CNR1GPR119NR1H2DPP4ALDH1A1
SCHEMBL25816276 0.86 SMN1; SMN2 (0.46) CNR1GPR119DPP4ALDH1A1L3MBTL1
SCHEMBL660403 0.86 NR1H2 (0.53) GPR119NR1H2ALDH1A1L3MBTL1SMN1; SMN2
SCHEMBL29508938 0.86 NR1H2 (0.53) GPR119NR1H2ALDH1A1L3MBTL1SMN1; SMN2
SCHEMBL31334725 0.86 ACHE (0.43) ALDH1A1SMN1; SMN2MAPTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4709720-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN Larkspur Biosciences, Inc. (US) 2026-03-18 EP disclosed
EP-4640686-A1 DEGRADER FOR DEGRADING BRD PROTEIN AND PHARMACEUTICAL COMPOSITION CONTAINING SAME Innocure Therapeutics, Inc. (KR) 2025-10-29 EP disclosed
EP-4624466-A1 DEGRADER FOR DECOMPOSING CMET PROTEIN, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME Innocure Therapeutics, Inc. (KR) 2025-10-01 EP disclosed
EP-4624472-A1 DEGRADER INCLUDING NOVEL C-MET PROTEIN LIGAND AND PHARMACEUTICAL COMPOSITION INCLUDING SAME Innocure Therapeutics, Inc. (KR) 2025-10-01 EP disclosed
US-20250034096-A1 COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF ANDROGEN RECEPTOR ARVINAS OPERATIONS, INC. 2025-01-30 US disclosed
WO-2024233846-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN LARKSPUR BIOSCIENCES, INC. (US) 2024-11-14 WO disclosed
WO-2024112120-A1 DEGRADER INCLUDING NOVEL C-MET PROTEIN LIGAND AND PHARMACEUTICAL COMPOSITION INCLUDING SAME 주식회사 이노큐어테라퓨틱스 2024-05-30 WO disclosed
WO-2024112119-A1 DEGRADER FOR DECOMPOSING CMET PROTEIN, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME 주식회사 이노큐어테라퓨틱스 2024-05-30 WO disclosed
WO-2024112122-A1 DEGRADER FOR DEGRADING BRD PROTEIN AND PHARMACEUTICAL COMPOSITION CONTAINING SAME 주식회사 이노큐어테라퓨틱스 2024-05-30 WO disclosed
CN-111892577-B Compounds and methods for androgen receptor targeted degradation 阿尔维纳斯运营股份有限公司 2023-07-07 CN disclosed
CN-111892577-A Compounds and methods for targeted degradation of androgen receptor 阿尔维纳斯运营股份有限公司 2020-11-06 CN disclosed
US-10584101-B2 Compounds and methods for the targeted degradation of androgen receptor Arvinas, Inc. (US) 2020-03-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250034096-A1 COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF ANDROGEN RECEPTOR AR, ADRM1, CRBN CNR1 1098/4885GPR119 887/4885NR1H2 490/4885
US-10584101-B2 Compounds and methods for the targeted degradation of androgen receptor AR, ADRM1, CRBN CNR1 1136/4885GPR119 866/4885NR1H2 514/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.