Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NPY1R | P25929 | 2/20 | 0.37 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MMP2 | P08253 | 6/20 | 0.37 |
| ▸ | MMP3 | P08254 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HPGDS | O60760 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21787144 | 0.91 | ALDH1A1 (0.43) | MMETSHRNPY1RNPY5RPOLB | |
| SCHEMBL21081674 | 0.91 | ALDH1A1 (0.43) | MMETSHRNPY1RNPY5RPOLB | |
| SCHEMBL21787357 | 0.86 | HTR2A (0.44) | MMETSHRNPY1RNPY5RPOLB | |
| SCHEMBL24677905 | 0.85 | TSHR (0.39) | MMETSHRNPY1RNPY5RPOLB | |
| SCHEMBL22799503 | 0.84 | KDM1A (0.40) | MMETSHRNPY1RNPY5RPOLB | |
| SCHEMBL24221036 | 0.82 | OPRK1 (0.36) | MMETSHRNPY1RNPY5RPOLB | |
| SCHEMBL23052535 | 0.81 | MME (0.43) | MMETSHRNPY1RNPY5RPOLB | |
| SCHEMBL21081697 | 0.81 | MME (0.43) | MMETSHRNPY1RNPY5RPOLB | |
| SCHEMBL21081676 | 0.81 | KDM1A (0.38) | MMETSHRNPY1RNPY5RPOLB | |
| SCHEMBL21081701 | 0.80 | MME (0.35) | MMETSHRNPY1RNPY5RPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200069810-A1 | THERAPEUTIC DENDRIMERS | ASTRAZENECA PHARMACEUTICALS LP | 2020-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200069810-A1 | THERAPEUTIC DENDRIMERS | CD44, ITGAV, FOLR1 | MME 2475/4885TSHR 2456/4885NPY1R 3400/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.