Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TLR2 | O60603 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.39 |
| ▸ | NAAA | Q02083 | 2/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | NPY1R | P25929 | 2/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21081697 | 1.00 | MME (0.43) | MMEKDM4EALDH1A1POLBTLR2 | |
| SCHEMBL21081674 | 0.89 | ALDH1A1 (0.43) | MMEKDM4EALDH1A1POLBNPSR1 | |
| SCHEMBL21787144 | 0.89 | ALDH1A1 (0.43) | MMEKDM4EALDH1A1POLBNPSR1 | |
| SCHEMBL24220982 | 0.89 | FOLH1 (0.44) | MMEALDH1A1POLBTLR2NPSR1 | |
| SCHEMBL24677819 | 0.89 | HTR2A (0.44) | MMEALDH1A1POLBTLR2NPSR1 | |
| SCHEMBL24677893 | 0.86 | NPSR1 (0.45) | MMEALDH1A1POLBTLR2NPSR1 | |
| SCHEMBL22799503 | 0.81 | KDM1A (0.40) | MMEPOLBNPSR1MEN1KMT2A | |
| SCHEMBL23052581 | 0.81 | KDM4E (0.42) | MMEKDM4EALDH1A1POLBTLR2 | |
| SCHEMBL21787147 | 0.81 | MME (0.39) | MMEKDM4EALDH1A1POLBNPSR1 | |
| SCHEMBL24221036 | 0.79 | OPRK1 (0.36) | MMEKDM4EALDH1A1POLBNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11717574-B2 | Therapeutic dendrimers | ASTRAZENECA AB (SE) | 2023-08-08 | — | — | US | disclosed |
| US-20210060172-A1 | THERAPEUTIC DENDRIMERS | ASTRAZENECA AB (SE) | 2021-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11717574-B2 | Therapeutic dendrimers | CD44, ITGAV, FOLR1 | MME 2475/4885KDM4E 4646/4885ALDH1A1 342/4885 |
| US-20210060172-A1 | THERAPEUTIC DENDRIMERS | CD44, ITGAV, FOLR1 | MME 2475/4885KDM4E 4646/4885ALDH1A1 342/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.