Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21777867 | 0.83 | ALOX15 (0.33) | ALOX15ALOX12 | |
| SCHEMBL21777868 | 0.81 | ALOX15 (0.34) | ALOX15ALOX12 | |
| SCHEMBL22863897 | 0.74 | — | — | |
| SCHEMBL21777253 | 0.69 | NPC1 (0.30) | — | |
| SCHEMBL5516808 | 0.67 | MAPT (0.32) | — | |
| SCHEMBL21787507 | 0.67 | MAPT (0.32) | — | |
| SCHEMBL5554079 | 0.63 | — | — | |
| SCHEMBL22863861 | 0.63 | ALDH1A1 (0.39) | — | |
| SCHEMBL21777252 | 0.63 | CYP1A2 (0.37) | — | |
| SCHEMBL8622111 | 0.62 | TRPA1 (0.71) | TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020047207-A1 | INHIBITORS OF (ALPHA-V)(BETA-6) INTEGRIN | MORPHIC THERAPEUTICS, INC. (US) | 2020-03-05 | — | — | WO | disclosed |