Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 2/20 | 0.34 |
| ▸ | MME | P08473 | 2/20 | 0.32 |
| ▸ | CPA1 | P15085 | 2/20 | 0.30 |
| ▸ | CPB1 | P15086 | 1/20 | 0.30 |
| ▸ | CPA3 | P15088 | 1/20 | 0.30 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12227950 | 0.85 | FOLH1 (0.42) | FOLH1MMECPA1CPB1CPA3 | |
| SCHEMBL12227951 | 0.82 | FOLH1 (0.37) | FOLH1MMECPA1CPB1CPA3 | |
| SCHEMBL21787485 | 0.81 | FOLH1 (0.36) | FOLH1MMECPA1CPB1CPA3 | |
| SCHEMBL21787487 | 0.79 | FOLH1 (0.35) | FOLH1MMECPA1CPB1CPA3 | |
| SCHEMBL12227947 | 0.75 | FOLH1 (0.39) | FOLH1MMECPA1CPB1CPA3 | |
| SCHEMBL21787488 | 0.75 | FOLH1 (0.39) | FOLH1MMECPA1CPB1CPA3 | |
| SCHEMBL11307033 | 0.66 | FOLH1 (0.47) | FOLH1MMECPA1CPB1CPA3 | |
| SCHEMBL18842300 | 0.66 | FOLH1 (0.48) | FOLH1MMECPA1CPB1CPA3 | |
| SCHEMBL4864369 | 0.66 | FOLH1 (0.48) | FOLH1MMECPA1CPB1CPA3 | |
| SCHEMBL10259513 | 0.64 | FOLH1 (0.46) | FOLH1MMECPA1CPB1CPA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210246344-A1 | Biological buffers with wide buffering ranges | DALY THOMAS (US) | 2021-08-12 | — | — | US | disclosed |
| US-20200071582-A1 | Biological Buffers with Wide Buffering Ranges | TPAT IP LLC | 2020-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200071582-A1 | Biological Buffers with Wide Buffering Ranges | PEF1, SLC7A1, PLPBP | FOLH1 685/4885MME 941/4885CPA1 380/4885 |
| US-20210246344-A1 | Biological buffers with wide buffering ranges | PEF1, SLC7A1, PLPBP | FOLH1 714/4885MME 990/4885CPA1 407/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.