Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 2/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CPA1 | P15085 | 2/20 | 0.34 |
| ▸ | CPB1 | P15086 | 1/20 | 0.34 |
| ▸ | CPA3 | P15088 | 1/20 | 0.34 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.34 |
| ▸ | MME | P08473 | 2/20 | 0.33 |
| ▸ | MMP2 | P08253 | 5/20 | 0.31 |
| ▸ | MMP3 | P08254 | 5/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12227951 | 0.87 | FOLH1 (0.37) | FOLH1CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL12227950 | 0.86 | FOLH1 (0.42) | FOLH1TDP1CPA1CPB1CPA3 | |
| SCHEMBL21787486 | 0.79 | FOLH1 (0.34) | FOLH1CPA1CPB1CPA3CPB2 | |
| SCHEMBL21787488 | 0.76 | FOLH1 (0.39) | FOLH1TDP1CPA1CPB1CPA3 | |
| SCHEMBL12227947 | 0.76 | FOLH1 (0.39) | FOLH1TDP1CPA1CPB1CPA3 | |
| SCHEMBL11307033 | 0.67 | FOLH1 (0.47) | FOLH1CPA1CPB1CPA3CPB2 | |
| SCHEMBL18842300 | 0.67 | FOLH1 (0.48) | FOLH1CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL24842643 | 0.66 | CHRM1 (0.35) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL21787485 | 0.66 | FOLH1 (0.36) | FOLH1SLC6A3TDP1CPA1CPB1 | |
| SCHEMBL12227953 | 0.65 | LMNA (0.45) | FOLH1CHRM1AKR1A1CHRM3HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210246344-A1 | Biological buffers with wide buffering ranges | DALY THOMAS (US) | 2021-08-12 | — | — | US | disclosed |
| US-20200071582-A1 | Biological Buffers with Wide Buffering Ranges | TPAT IP LLC | 2020-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200071582-A1 | Biological Buffers with Wide Buffering Ranges | PEF1, SLC7A1, PLPBP | FOLH1 685/4885CHRM1 2714/4885AKR1A1 2325/4885 |
| US-20210246344-A1 | Biological buffers with wide buffering ranges | PEF1, SLC7A1, PLPBP | FOLH1 714/4885CHRM1 2762/4885AKR1A1 2314/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.