Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 3/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.37 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24007719 | 0.75 | BRD4 (0.51) | TAS1R3TAS1R1ALDH1A1KMT2AHTT | |
| SCHEMBL24006876 | 0.75 | BRD4 (0.48) | TAS1R3TAS1R1DUSP3KMT2APTPN11 | |
| SCHEMBL21787795 | 0.71 | TAS1R3 (0.40) | TAS1R3TAS1R1LMNAALDH1A1MAPT | |
| SCHEMBL21787947 | 0.70 | ALDH1A1 (0.39) | TAS1R3TAS1R1LMNAMAOBALDH1A1 | |
| SCHEMBL15641270 | 0.69 | AKR1C3 (0.63) | TAS1R3TAS1R1LMNAALDH1A1TSHR | |
| SCHEMBL15641272 | 0.69 | AKR1C3 (0.63) | TAS1R3TAS1R1LMNAALDH1A1TSHR | |
| SCHEMBL15943184 | 0.68 | TAS1R3 (0.48) | TAS1R3TAS1R1LMNAALDH1A1MAPT | |
| SCHEMBL14905539 | 0.68 | TAS1R3 (0.46) | TAS1R3TAS1R1LMNAALDH1A1MAPT | |
| SCHEMBL14905538 | 0.68 | TAS1R3 (0.46) | TAS1R3TAS1R1LMNAALDH1A1MAPT | |
| SCHEMBL2670001 | 0.68 | HDAC4 (0.47) | TAS1R3TAS1R1LMNARECQLALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020043821-A1 | FURAN DERIVATIVES AS BROMODOMAIN INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED (GB) | 2020-03-05 | — | — | WO | disclosed |