Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 4/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ERN1 | O75460 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24006876 | 0.81 | BRD4 (0.48) | TAS1R3TAS1R1KMT2A | |
| SCHEMBL21787947 | 0.79 | ALDH1A1 (0.39) | TAS1R3TAS1R1ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL24007719 | 0.73 | BRD4 (0.51) | TAS1R3TAS1R1ALDH1A1HTTMEN1 | |
| SCHEMBL21787802 | 0.71 | TAS1R3 (0.44) | TAS1R3TAS1R1ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL21787787 | 0.69 | ALDH1A1 (0.47) | ALDH1A1HTTSMN1; SMN2GAALMNA | |
| SCHEMBL74642 | 0.67 | PDE4A (0.44) | ALDH1A1SMN1; SMN2LMNAHPGDKDM4E | |
| SCHEMBL15641272 | 0.65 | AKR1C3 (0.63) | TAS1R3TAS1R1ALDH1A1LMNA | |
| SCHEMBL15641270 | 0.65 | AKR1C3 (0.63) | TAS1R3TAS1R1ALDH1A1LMNA | |
| SCHEMBL21788050 | 0.65 | BRD4 (0.48) | ALDH1A1GAAPOLBNPSR1 | |
| SCHEMBL18920576 | 0.65 | ALDH1A1 (0.63) | ALDH1A1SMN1; SMN2GAALMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020043821-A1 | FURAN DERIVATIVES AS BROMODOMAIN INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED (GB) | 2020-03-05 | — | — | WO | disclosed |