SCHEMBL21788435

SCHEMBL21788435

CCC(N)C1CCC(c2ccc(C)cc2)CC1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC18A3 Q16572 2/20 0.36
SPHK1 Q9NYA1 1/20 0.36
CYP2C9 P11712 2/20 0.36
HTR2A P28223 1/20 0.35
HTR2C P28335 1/20 0.35
HTR2B P41595 1/20 0.35
ESR2 Q92731 2/20 0.34
ALDH1A1 P00352 2/20 0.34
LMNA P02545 2/20 0.34
MAPT P10636 2/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
TP53 P04637 1/20 0.34
ATM Q13315 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
MAPK1 P28482 1/20 0.34
DRD2 P14416 2/20 0.33
ESR1 P03372 1/20 0.33
CYP3A4 P08684 1/20 0.33
IDO1 P14902 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18458889 0.95 SLC18A3 (0.34) SLC18A3SPHK1CYP2C9HTR2AHTR2C
SCHEMBL18458911 0.85 DRD2 (0.49) CYP2C9LMNAMAPTMEN1KMT2A
SCHEMBL18458822 0.82 SPHK1 (0.47) SLC18A3SPHK1CYP2C9ESR2ALDH1A1
SCHEMBL19619424 0.82 SPHK1 (0.47) SLC18A3SPHK1CYP2C9ESR2ALDH1A1
SCHEMBL18512739 0.82 DRD2 (0.50) HTR2CALDH1A1MAPTMEN1KMT2A
SCHEMBL18800271 0.82 SLC18A3 (0.34) SLC18A3SPHK1CYP2C9ESR2ALDH1A1
SCHEMBL18458501 0.81 SPHK1 (0.39) SPHK1CYP2C9
SCHEMBL20160936 0.81 GRIA1 (0.51) MEN1KMT2AMAPK1DRD2DRD3
SCHEMBL20929628 0.81 SPHK1 (0.39) SPHK1CYP2C9ALDH1A1LMNAMAPT
SCHEMBL18458741 0.81 DPP4 (0.40) SPHK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020116555-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT DIC株式会社 2020-06-11 WO disclosed
WO-2020044833-A1 LIQUID CRYSTAL COMPOSITION DIC株式会社 2020-03-05 WO disclosed