Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17265919 | 0.71 | — | — | |
| SCHEMBL17209841 | 0.70 | — | — | |
| SCHEMBL4020797 | 0.70 | — | — | |
| SCHEMBL5671901 | 0.69 | — | — | |
| SCHEMBL16326843 | 0.69 | — | — | |
| SCHEMBL20442005 | 0.65 | — | — | |
| SCHEMBL15597368 | 0.64 | NFKB1 (0.39) | — | |
| SCHEMBL24233252 | 0.63 | L3MBTL1 (0.38) | LMNA | |
| SCHEMBL5670996 | 0.63 | CA2 (0.40) | — | |
| SCHEMBL19145814 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020047251-A1 | O-GLCNAC TRANSFERASE INHIBITORS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2020-03-05 | — | — | WO | disclosed |