Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21789031 | 0.85 | TOP2A (0.33) | HSD11B1TOP2A | |
| SCHEMBL21788880 | 0.77 | TOP2A (0.40) | HSD11B1TOP2A | |
| SCHEMBL30354018 | 0.75 | MAPT (0.30) | — | |
| SCHEMBL23161288 | 0.72 | SCN9A (0.32) | — | |
| SCHEMBL26938720 | 0.72 | ALDH1A1 (0.32) | HSD11B1 | |
| SCHEMBL20971974 | 0.71 | — | — | |
| SCHEMBL1809028 | 0.70 | FKBP1A (0.35) | — | |
| SCHEMBL25568333 | 0.69 | MAPT (0.31) | — | |
| SCHEMBL25568332 | 0.69 | MAPT (0.31) | — | |
| SCHEMBL15569884 | 0.69 | FKBP1A (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020047447-A1 | CARDIAC SARCOMERE INHIBITORS | CYTOKINETICS, INC. (US) | 2020-03-05 | — | — | WO | disclosed |