Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | ACACB | O00763 | 1/20 | 0.52 |
| ▸ | ACACA | Q13085 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1697719 | 1.00 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2POLBNPSR1LMNA | |
| SCHEMBL1697716 | 1.00 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2POLBNPSR1LMNA | |
| SCHEMBL10066478 | 0.86 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2POLBNPSR1LMNA | |
| SCHEMBL9953212 | 0.86 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2POLBNPSR1LMNA | |
| SCHEMBL7929055 | 0.84 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2POLBNPSR1LMNA | |
| SCHEMBL19658757 | 0.82 | HTT (0.71) | ALDH1A1LMNAACACBACACAMEN1 | |
| SCHEMBL14535437 | 0.82 | HTT (0.71) | ALDH1A1LMNAACACBACACAMEN1 | |
| SCHEMBL8445815 | 0.82 | GPR139 (0.55) | ALDH1A1SMN1; SMN2LMNAACACBACACA | |
| SCHEMBL12975787 | 0.81 | MAPT (0.65) | ALDH1A1POLBMEN1KMT2AGAA | |
| SCHEMBL12975495 | 0.81 | MAPT (0.65) | ALDH1A1POLBMEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102844299-B | Desinsection aryl-pyrrolidine alkane | BAYER CROPSCIENCE AG (DE) | 2016-03-30 | — | — | CN | disclosed |
| EP-2519499-B1 | PESTICIDAL ARYLPYRROLIDINES | BAYER IP GMBH (DE) | 2013-09-18 | — | — | EP | disclosed |
| US-8536201-B2 | Pesticidal arylpyrrolidines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-09-17 | — | — | US | disclosed |
| CN-102844299-A | Pesticidal arylpyrrolidines | BAYER CROPSCIENCE AG | 2012-12-26 | — | — | CN | disclosed |
| US-20120322833-A1 | Pesticidal Arylpyrrolidines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2012-12-20 | — | — | US | disclosed |
| EP-2519499-A1 | PESTICIDAL ARYLPYRROLIDINES | Bayer Intellectual Property GmbH (DE) | 2012-11-07 | — | — | EP | disclosed |
| WO-2011080211-A1 | PESTICIDAL ARYLPYRROLIDINES | BAYER CROPSCIENCE AG (DE) | 2011-07-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120322833-A1 | Pesticidal Arylpyrrolidines | DDT, CYP4X1, CHRM2 | ALDH1A1 1542/4885SMN1; SMN2 3354/4885POLB 4785/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.