SCHEMBL21790496

SCHEMBL21790496

Cc1cc(-c2ccc(OC(=O)Oc3ccc(-c4ccc(OC(=O)Oc5ccccc5)c(C)c4)cc3C)c(C)c2)ccc1OC(=O)Oc1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PPARG P37231 3/20 0.46
PPARA Q07869 2/20 0.46
MRGPRX4 Q96LA9 1/20 0.44
HPGD P15428 1/20 0.43
MAPT P10636 4/20 0.42
TDP1 Q9NUW8 1/20 0.42
PPARD Q03181 1/20 0.42
POLB P06746 2/20 0.40
CFD P00746 1/20 0.40
USP2 O75604 1/20 0.40
LMNA P02545 1/20 0.39
GAA P10253 1/20 0.39
ALDH1A1 P00352 2/20 0.38
KMT2A Q03164 1/20 0.38
NCOA2 Q15596 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
RXFP1 Q9HBX9 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21790495 1.00 PPARG (0.46) PPARGPPARAMRGPRX4HPGDMAPT
SCHEMBL21790500 0.93 HSD17B1 (0.43) PPARGPPARAMRGPRX4HPGDMAPT
SCHEMBL21790499 0.93 HSD17B1 (0.43) PPARGPPARAMRGPRX4HPGDMAPT
SCHEMBL2345746 0.87 L3MBTL1 (0.48) MRGPRX4HPGDMAPTTDP1POLB
SCHEMBL16394993 0.83 MAPT (0.42) PPARGMRGPRX4HPGDMAPTTDP1
SCHEMBL31105782 0.82 ATM (0.47) PPARGHPGDMAPTTDP1USP2
SCHEMBL361382 0.82 ATM (0.47) PPARGHPGDMAPTTDP1USP2
SCHEMBL4447619 0.82 ATM (0.47) PPARGHPGDMAPTTDP1USP2
SCHEMBL7571401 0.80 PPARG (0.52) PPARGPPARAMRGPRX4HPGDMAPT
SCHEMBL21790498 0.79 HSD17B1 (0.47) PPARGPPARATDP1CFD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11130840-B2 Aromatic polycarbonate oligomer solid HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2021-09-28 US disclosed
US-20200071460-A1 AROMATIC POLYCARBONATE OLIGOMER SOLID HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2020-03-05 US disclosed