SCHEMBL7571401

SCHEMBL7571401

CCOC(=O)Oc1ccc(-c2ccccc2)cc1C

nearest known ligand 0.52

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PPARG P37231 3/20 0.52
PPARA Q07869 3/20 0.52
MRGPRX4 Q96LA9 1/20 0.50
PPARD Q03181 1/20 0.45
TARBP2 Q15633 1/20 0.44
ALOX5 P09917 1/20 0.43
DHODH Q02127 1/20 0.43
RXRA P19793 1/20 0.41
RXRB P28702 1/20 0.41
TYMS P04818 1/20 0.41
SLC6A9 P48067 1/20 0.41
ALDH1A1 P00352 1/20 0.41
MAPT P10636 1/20 0.41
HPGD P15428 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6222370 0.87 ALPL (0.43) PPARGPPARAPPARDTARBP2ALOX5
SCHEMBL7571353 0.85 CYP1A2 (0.46) PPARGPPARATARBP2ALOX5DHODH
SCHEMBL7578265 0.83 ALOX5 (0.48) PPARGPPARAPPARDTARBP2ALOX5
SCHEMBL21790496 0.80 PPARG (0.46) PPARGPPARAMRGPRX4PPARDALDH1A1
SCHEMBL21790495 0.80 PPARG (0.46) PPARGPPARAMRGPRX4PPARDALDH1A1
SCHEMBL1598817 0.79 SMN1; SMN2 (0.51) MRGPRX4TYMSALDH1A1MAPTHPGD
SCHEMBL6976915 0.79 NPC1 (0.51) TARBP2ALOX5ALDH1A1MAPTHPGD
SCHEMBL1598707 0.79 TDP1 (0.51) PPARGRXRARXRBTYMSALDH1A1
SCHEMBL10501271 0.78 ALDH1A1 (0.46) TARBP2ALOX5ALDH1A1MAPTHPGD
SCHEMBL1911874 0.77 MRGPRX4 (0.54) PPARGPPARAMRGPRX4PPARDRXRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020086892-A1 For controlling animal pests, in particular: insects, arachnids and nematodes BAYER AKTIENGESELLSCHAFT (DE) 2002-07-04 US disclosed
US-6410581-B1 INSECTICIDES, MITICIDES, NEMATOCIDES BAYER AKTIENGESELLSCHAFT (DE) 2002-06-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020086892-A1 For controlling animal pests, in particular: insects, arachnids and nematodes ATXN2, HAX1, ANTXR2 PPARG 4297/4885PPARA 4505/4885MRGPRX4 122/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.