Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 12/20 | 0.40 |
| ▸ | NAMPT | P43490 | 8/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2179056 | 0.78 | GCK (0.47) | GCK | |
| SCHEMBL2179866 | 0.76 | GSR (0.37) | GCKNAMPTCYP2C9 | |
| SCHEMBL2178449 | 0.73 | PIK3C3 (0.37) | GCKNAMPTCYP2C9 | |
| SCHEMBL2180005 | 0.72 | GCK (0.40) | GCK | |
| SCHEMBL2196374 | 0.69 | GCK (0.51) | GCKNAMPT | |
| SCHEMBL2280345 | 0.67 | GCK (0.47) | GCKNAMPT | |
| SCHEMBL2280341 | 0.67 | GCK (0.47) | GCKNAMPT | |
| SCHEMBL2180026 | 0.66 | GCK (0.48) | GCK | |
| SCHEMBL2198514 | 0.66 | GCK (0.50) | GCKNAMPT | |
| SCHEMBL2178179 | 0.65 | ALDH1A1 (0.34) | GCKNAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011080755-A1 | FUSED NITROGEN HETEROCYCLIC COMPOUNDS, PROCESS OF PREPARATION AND USES THEREOF | ADVINUS THERAPEUTICS PRIVATE LIMITED (IN) | 2011-07-07 | — | — | WO | claimed |
| WO-2011080755-A1 | FUSED NITROGEN HETEROCYCLIC COMPOUNDS, PROCESS OF PREPARATION AND USES THEREOF | ADVINUS THERAPEUTICS PRIVATE LIMITED (IN) | 2011-07-07 | — | — | WO | disclosed |