Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GCK | P35557 | 8/20 | 0.32 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NAMPT | P43490 | 3/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.31 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.31 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.31 |
| ▸ | S100A9 | P06702 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2178449 | 0.85 | PIK3C3 (0.37) | GCKLNPEPNAMPTPIK3C3 | |
| SCHEMBL2178622 | 0.79 | NAMPT (0.34) | GCKLNPEPNAMPTEGLN2EGLN1 | |
| SCHEMBL2178177 | 0.78 | GCK (0.47) | GCKLNPEP | |
| SCHEMBL2179866 | 0.77 | GSR (0.37) | ALDH1A1GCKMEN1KMT2ANAMPT | |
| SCHEMBL2179066 | 0.75 | EGLN2 (0.39) | GCKLNPEPNAMPTEGLN2EGLN1 | |
| SCHEMBL2178527 | 0.72 | GCK (0.35) | GCK | |
| SCHEMBL2180005 | 0.69 | GCK (0.40) | GCK | |
| SCHEMBL2178905 | 0.69 | GCK (0.38) | GCKNAMPTCNR1 | |
| SCHEMBL2180161 | 0.68 | NAMPT (0.37) | ALDH1A1MEN1KMT2ANAMPT | |
| SCHEMBL2179681 | 0.67 | GCK (0.48) | GCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011080755-A1 | FUSED NITROGEN HETEROCYCLIC COMPOUNDS, PROCESS OF PREPARATION AND USES THEREOF | ADVINUS THERAPEUTICS PRIVATE LIMITED (IN) | 2011-07-07 | — | — | WO | disclosed |