Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.37 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.36 |
| ▸ | GCK | P35557 | 9/20 | 0.34 |
| ▸ | NAMPT | P43490 | 7/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
| ▸ | KDM5A | P29375 | 1/20 | 0.31 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2178179 | 0.85 | ALDH1A1 (0.34) | PIK3C3LNPEPGCKNAMPT | |
| SCHEMBL2180005 | 0.83 | GCK (0.40) | GCK | |
| SCHEMBL2178622 | 0.79 | NAMPT (0.34) | PIK3C3LNPEPGCKNAMPTCYP2C9 | |
| SCHEMBL2178444 | 0.76 | GCK (0.50) | LNPEPGCK | |
| SCHEMBL2179066 | 0.75 | EGLN2 (0.39) | PIK3C3LNPEPGCKNAMPTCYP2C9 | |
| SCHEMBL2179060 | 0.73 | GCK (0.40) | GCKNAMPTCYP2C9 | |
| SCHEMBL2177869 | 0.72 | GCK (0.44) | PIK3C3LNPEPGCK | |
| SCHEMBL2179866 | 0.71 | GSR (0.37) | PIK3C3GCKNAMPTCYP2C9 | |
| SCHEMBL2039421 | 0.68 | GCK (0.39) | GCK | |
| SCHEMBL2178527 | 0.68 | GCK (0.35) | GCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011080755-A1 | FUSED NITROGEN HETEROCYCLIC COMPOUNDS, PROCESS OF PREPARATION AND USES THEREOF | ADVINUS THERAPEUTICS PRIVATE LIMITED (IN) | 2011-07-07 | — | — | WO | disclosed |