Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9781352 | 0.85 | ALDH1A1 (0.51) | ALDH1A1L3MBTL1TSHRCYP3A4ALOX15 | |
| SCHEMBL17604272 | 0.85 | MAPT (0.49) | ALDH1A1L3MBTL1TSHRTP53MAPT | |
| SCHEMBL3875112 | 0.83 | MEN1 (0.53) | ALDH1A1L3MBTL1TSHRSMN1; SMN2MAPT | |
| SCHEMBL2963582 | 0.83 | ALDH1A1 (0.67) | ALDH1A1L3MBTL1TSHRSMN1; SMN2TP53 | |
| SCHEMBL631776 | 0.82 | KCNH3 (0.64) | ALDH1A1L3MBTL1TSHRSMN1; SMN2TP53 | |
| Hydrochloric Acid SCHEMBL2249099 | 0.80 | KCNH3 (0.67) | ALDH1A1L3MBTL1TSHRTP53THRB | |
| SCHEMBL2704334 | 0.80 | TSHR (0.53) | ALDH1A1TSHRTP53MEN1KMT2A | |
| SCHEMBL10989610 | 0.79 | KCNH3 (0.53) | ALDH1A1L3MBTL1TSHRSMN1; SMN2TP53 | |
| SCHEMBL28885886 | 0.79 | KCNH3 (0.53) | ALDH1A1L3MBTL1TSHRSMN1; SMN2TP53 | |
| SCHEMBL21780495 | 0.78 | ALDH1A1 (0.59) | ALDH1A1L3MBTL1TSHRSMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200071308-A1 | Benzene, Pyridine, and Pyridazine Derivatives | ESANEX INC (US) | 2020-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200071308-A1 | Benzene, Pyridine, and Pyridazine Derivatives | CDK4, P2RX4, MKI67 | ALDH1A1 1049/4885L3MBTL1 3811/4885TSHR 1413/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.