Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21790727 | 0.83 | ALDH1A1 (0.52) | MEN1KMT2AMAPTGAANPSR1 | |
| SCHEMBL9781352 | 0.82 | ALDH1A1 (0.51) | MEN1KMT2AMAPTGAANPSR1 | |
| SCHEMBL17604272 | 0.82 | MAPT (0.49) | MEN1KMT2AMAPTGAANPSR1 | |
| SCHEMBL631776 | 0.79 | KCNH3 (0.64) | MEN1KMT2AMAPTKCNH3ALDH1A1 | |
| Hydrochloric Acid SCHEMBL2249099 | 0.78 | KCNH3 (0.67) | MEN1KMT2AMAPTKCNH3ALDH1A1 | |
| SCHEMBL2704334 | 0.77 | TSHR (0.53) | MEN1KMT2AALDH1A1POLBMTNR1B | |
| SCHEMBL28885886 | 0.76 | KCNH3 (0.53) | MEN1KMT2AMAPTKCNH3ALDH1A1 | |
| SCHEMBL10989610 | 0.76 | KCNH3 (0.53) | MEN1KMT2AMAPTGAAKCNH3 | |
| SCHEMBL2918668 | 0.75 | TDP1 (0.54) | GAANPSR1KCNH3ALDH1A1L3MBTL1 | |
| SCHEMBL3650245 | 0.73 | MTNR1A (0.41) | MEN1KMT2AMAPTGAANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2118076-A1 | QUINOXALINE COMPOUNDS AND USE THEREOF | Merck Serono S.A. (CH) | 2009-11-18 | — | — | EP | disclosed |
| WO-2008101979-A1 | QUINOXALINE COMPOUNDS AND USE THEREOF | MERCK SERONO S.A. (CH) | 2008-08-28 | — | — | WO | disclosed |