Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11751773 | 0.90 | CYP2D6 (0.48) | CYP2D6LMNACYP3A4MAPTKDM4E | |
| SCHEMBL9858071 | 0.87 | EPHX2 (0.45) | CYP2D6LMNACYP3A4MAPTKDM4E | |
| SCHEMBL11747108 | 0.86 | CYP2D6 (0.45) | CYP2D6LMNACYP3A4MAPTKDM4E | |
| SCHEMBL2369686 | 0.85 | EPHX2 (0.47) | MEN1KMT2ATP53HTTEPHX2 | |
| SCHEMBL5606363 | 0.85 | EPHX2 (0.47) | MEN1KMT2ATP53HTTEPHX2 | |
| SCHEMBL5071108 | 0.85 | EPHX2 (0.47) | MEN1KMT2ATP53HTTEPHX2 | |
| SCHEMBL2370129 | 0.85 | EPHX2 (0.47) | MEN1KMT2ATP53HTTEPHX2 | |
| SCHEMBL5608113 | 0.84 | SSTR4 (0.44) | CYP2D6LMNACYP3A4MAPTKDM4E | |
| Hydrochloric Acid SCHEMBL2232233 | 0.84 | EPHX2 (0.46) | CYP3A4MAPTKDM4EMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL356747 | 0.84 | EPHX2 (0.46) | CYP3A4MAPTKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10716791-B2 | Inhibitors of peptidyl arginine deiminase (PAD) enzymes and uses thereof | UNIVERSITY HEALTH NETWORK (CA) | 2020-07-21 | — | — | US | disclosed |
| US-20200071308-A1 | Benzene, Pyridine, and Pyridazine Derivatives | ESANEX INC (US) | 2020-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10716791-B2 | Inhibitors of peptidyl arginine deiminase (PAD) enzymes and uses thereof | PADI2, PADI1, PADI4 | CYP2D6 1508/4885LMNA 3902/4885CYP3A4 2376/4885 |
| US-20200071308-A1 | Benzene, Pyridine, and Pyridazine Derivatives | CDK4, P2RX4, MKI67 | CYP2D6 209/4885LMNA 2839/4885CYP3A4 45/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.