SCHEMBL21790995

SCHEMBL21790995

c1ccc2cc3c(cc2c1)c1c2ccccc2c2ccccc2c1n1c2ccccc2nc31

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 9/20 0.49
MAPT P10636 6/20 0.49
LMNA P02545 3/20 0.49
POLB P06746 3/20 0.49
HSD17B10 Q99714 3/20 0.49
TP53 P04637 2/20 0.49
HPGD P15428 6/20 0.48
ALDH1A1 P00352 6/20 0.48
KMT2A Q03164 5/20 0.46
MEN1 O00255 3/20 0.46
SMN1; SMN2 Q16637 3/20 0.43
BCL2 P10415 1/20 0.41
CYP1A2 P05177 2/20 0.40
CAMKK1 Q8N5S9 2/20 0.40
CAMKK2 Q96RR4 2/20 0.40
CYP2D6 P10635 1/20 0.40
CYP2C9 P11712 1/20 0.40
CASP1 P29466 1/20 0.40
CYP2C19 P33261 1/20 0.40
CASP7 P55210 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21917584 0.85 POLB (0.47) KDM4EMAPTLMNAPOLBHSD17B10
SCHEMBL21917585 0.84 KDM4E (0.46) KDM4EMAPTLMNAPOLBHSD17B10
SCHEMBL21298045 0.84 HPGD (0.38) KDM4EMAPTLMNAPOLBHSD17B10
SCHEMBL20561645 0.83 KDM4E (0.44) KDM4EMAPTLMNAPOLBHSD17B10
SCHEMBL19959763 0.82 KDM4E (0.49) KDM4EMAPTLMNAPOLBHSD17B10
SCHEMBL21297768 0.81 KDM4E (0.50) KDM4EMAPTLMNAPOLBHSD17B10
SCHEMBL19959757 0.81 KDM4E (0.54) KDM4EMAPTLMNAPOLBHSD17B10
SCHEMBL19959762 0.81 KDM4E (0.48) KDM4EMAPTLMNAPOLBHSD17B10
SCHEMBL21298223 0.81 KDM4E (0.48) KDM4EMAPTLMNAPOLBHSD17B10
SCHEMBL21297966 0.81 KDM4E (0.44) KDM4EMAPTLMNAPOLBHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230192695-A1 THERMALLY ASSISTED DELAYED FLUORESCENT MATERIALS WITH TRIAD-TYPE MATERIALS UNIV ARIZONA STATE (US) 2023-06-22 US disclosed
US-20230192695-A1 THERMALLY ASSISTED DELAYED FLUORESCENT MATERIALS WITH TRIAD-TYPE MATERIALS UNIV ARIZONA STATE (US) 2023-06-22 US disclosed
US-20210024526-A1 THERMALLY ASSISTED DELAYED FLUORESCENT MATERIALS WITH TRIAD-TYPE MATERIALS UNITED STATES DEPARTMENT OF ENERGY 2021-01-28 US disclosed
US-10851106-B2 Substituted benzo[4,5]imidazo[1,2-F]phenanthridines, dibenzo[I.K]benzo[4,5]imidazo[1,2-F]benzofurophenanthridines and dibenzo[I.K]benzo[4,5]imidazo[1,2-F]benzo[4,5]thienophenanthridines as thermally assisted delayed fluorescent materials ARIZONA BOARD OF REGENTS, ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2020-12-01 US disclosed
US-20200071330-A1 THERMALLY ASSISTED DELAYED FLUORESCENT MATERIALS WITH TRIAD-TYPE MATERIALS UNITED STATES DEPARTMENT OF ENERGY 2020-03-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210024526-A1 THERMALLY ASSISTED DELAYED FLUORESCENT MATERIALS WITH TRIAD-TYPE MATERIALS TTPA, TTC14, AAAS KDM4E 3740/4885MAPT 467/4885LMNA 1328/4885
US-20200071330-A1 THERMALLY ASSISTED DELAYED FLUORESCENT MATERIALS WITH TRIAD-TYPE MATERIALS TTPA, TTC14, AAAS KDM4E 3740/4885MAPT 467/4885LMNA 1328/4885
US-20230192695-A1 THERMALLY ASSISTED DELAYED FLUORESCENT MATERIALS WITH TRIAD-TYPE MATERIALS TTPA, TTC14, AAAS KDM4E 3740/4885MAPT 467/4885LMNA 1328/4885
US-10851106-B2 Substituted benzo[4,5]imidazo[1,2-F]phenanthridines, dibenzo[I.K]benzo[4,5]imidazo[1,2-F]benzofurophenanthridines and dibenzo[I.K]benzo[4,5]imidazo[1,2-F]benzo[4,5]thienophenanthridines as thermally assisted delayed fluorescent materials KCNK4, TRPC4, TBRG4 KDM4E 731/4885MAPT 1680/4885LMNA 1704/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.