Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | RRM1 | P23921 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 2/20 | 0.41 |
| ▸ | CTSK | P43235 | 2/20 | 0.41 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.40 |
| ▸ | KLK7 | P49862 | 1/20 | 0.40 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | TGM2 | P21980 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.39 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.39 |
| ▸ | ALB | P02768 | 1/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23921370 | 0.90 | SIRT5 (0.44) | SIRT5BCHEACHECXCR3SIRT2 | |
| SCHEMBL23921368 | 0.88 | KLK7 (0.42) | ALDH1A1TSHRGAASIRT5KLK7 | |
| SCHEMBL14238197 | 0.84 | CA1 (0.45) | ALDH1A1TSHRGAACTSKSIRT5 | |
| SCHEMBL26265633 | 0.84 | CA1 (0.45) | ALDH1A1TSHRGAACTSKSIRT5 | |
| SCHEMBL23921371 | 0.84 | BCHE (0.39) | SIRT5KLK7KLK5BCHEACHE | |
| SCHEMBL30852794 | 0.82 | RRM1 (0.44) | RRM1ALB | |
| SCHEMBL21713192 | 0.80 | CAPN1 (0.46) | ALDH1A1TSHRGAACTSKSIRT5 | |
| SCHEMBL31045346 | 0.80 | CAPN1 (0.46) | ALDH1A1TSHRGAACTSKSIRT5 | |
| SCHEMBL21713193 | 0.80 | CAPN1 (0.46) | ALDH1A1TSHRGAACTSKSIRT5 | |
| SCHEMBL27150954 | 0.80 | CAPN1 (0.46) | ALDH1A1TSHRGAACTSKSIRT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210317213-A1 | Anti-CD3 Antibody Folate Bioconjugates and Their Uses | AMBRX, INC. (US) | 2021-10-14 | — | — | US | disclosed |
| WO-2020047176-A1 | ANTI-CD3 ANTIBODY FOLATE BIOCONJUGATES AND THEIR USES | AMBRX, INC. (US) | 2020-03-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210317213-A1 | Anti-CD3 Antibody Folate Bioconjugates and Their Uses | FOLR2, FOLR1, CD2 | ALDH1A1 2499/4885TSHR 1044/4885RRM1 1994/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.